This experiment was conducted to study the effects of maize contaminated with naturally-occuring mycotoxins on growth performance, intestinal morphology, intestinal microbial populations and their metabolic products in piglets. Fifteen PIC piglets (35 days of age) were randomly allocated to 3 dietary treatments with 5 replicates per treatment and 1 piglet per replicate. Piglets in group 1 were fed a basal diet (normal maize, control group); piglets in group 2 were fed the diet with contaminated maize (normal maize in the group 1 was 100% replaced by mycotoxin-contaminated maize, contaminated maize group); group 3 was a pair-fed group. For the pair-fed group, the basal diet was pair-fed to piglets at the level of feed intake of piglets fed the contaminated maize diet. The trial lasted for 21 d. The results showed that contaminated maize trended to decrease the arerage daily gain (ADG) and arerage daily feed intake (ADFI) compared with the control group during the first two weeks (P>0.05), whereas during the whole trial period, ADG in the contaminated maize group was significantly higher and feed/gain ratio (F/G) was significantly lower than those in the pair-fed group (P<0.05). The ratio of villus height to crypt depth of jejunum in the contaminated maize group was significantly lower than that in the control and pair-fed group (P<0.05), and the crypt depth was significantly higher than that in the pair-fed group (P<0.05). Compared with the pair-fed group, the levels of acetic acid and total volatile fatty acids in rectum contents in the contaminated maize group were decreased significantly on the second weekend (P<0.05). On the third weekend, the number of Escherichia coli and Lactobacillus and the level of propionic acid in cecum contents in the contaminated maize group were significantly higher than those in the control group (P<0.05), and the concentration of ammonia trended to be increased (P>0.05). In conclusion, maize naturally contaminated with mycotoxins can damage mucosal morphology of jejunum, increase the number of Escherichia coli and Lactobacillus in cecum contents, break the balance of intestinal flora, and then influence the health of piglets.［Chinese Journal of Animal Nutrition, 2011, 23（10）：1790 -1799］
LEI Xiaoya,CHEN Daiwen,MAO Xiangbing,MAO Qian,CHEN Hong,ZHANG Ling,DUAN Xudong,YU Bing
. Effects of Maize Contaminated with Naturally-Occuring Mycotoxins on Intestinal Microecology in Piglets[J]. Chinese Journal of Animal Nutrition, 2011
, 23(10)
: 1790
-1799
.
DOI: 10.3969/j.issn.1006-267x.2011.10.020
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