Effects of Dietary Berberis Extract and Gamma Aminobutyric Acid on Growth Performance and Immune Function of Broilers

ZHANG Guanghui, XIE Jinhui, CHEN Pengju

doi:10.3969/j.issn.1006-267x.2011.11.020

Chinese Journal of Animal Nutrition >

2011 , Vol. 23 >Issue 11: 1984 - 1990

DOI: https://doi.org/10.3969/j.issn.1006-267x.2011.11.020

Feed Science and Technology

Effects of Dietary Berberis Extract and Gamma Aminobutyric Acid on Growth Performance and Immune Function of Broilers

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1. Engineering College of Animal Husbandry and Veterinary Science, Henan Agricultural University, Zhengzhou 450002, China;
2. Hefei Veterinary Preparations Engineering Research Center in Anhui Province, Hefei 231200, China;
3. Anhui Ruisen Biotechnology Co., Ltd., Hefei 231200, China

Received date: 2011-06-24

Online published: 2011-11-21

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Abstract

The experiment was conducted to study the effects of dietary Berberis extract and gamma aminobutyric acid on growth performance, nutrient apparent digestibility and immune function of broilers. A total of 240 one-day-old Arbor Acres broilers were divided into four groups with six replicates in each group and 10 broilers in each replicate. A single factor design was adopted, and broilers were fed a corn-soybean meal based diet with 0.20% Berberis extract, 0.01% gamma aminobutyric acid, 0.20% Berberis extract+0.01% gamma aminobutyric acid and 5 mg/kg avilamycin (control group), respectively. The experiment lasted for 7 weeks. Broilers obtained Newcastle Disease vaccines (HDV) at 7 and 21 days by drinking water, respectively, and the antibody was measured on the 7th and 14th day after immunization, and stimulation index (SI) challenged with ConA was measured at 14, 28 and 42 days. The results showed as follows: 1) there were no significant differences among all groups in the final weight, average daily gain and average daily feed intake of broilers (P>0.05). Feed/gain in the Berberis extract group was higher than that in the control group (P<0.05), but there was no significant difference between the gamma aminobutyric acid group and the control group (P>0.05), and the combined group was higher than the other groups (P<0.05). 2) The apparent digestibility of crude protein, crude fat, calcium and phosphorus in the Berberis extract group were significantly lower than those in the control group (P<0.01), but there were no significant differences among the control group, combined group and gamma aminobutyric acid group (P>0.05). 3) On the 7th day after the first immunization, there was no significant difference among all groups in serum HDV-HI of broilers (P>0.05), on the 14th day, the gamma aminobutyric acid group and the combined group were higher than the control group and Berberis extract group (P<0.05). On the 7th and 14th day after the second immunization, the serum HDV-HI of broilers in the combined group and gamma aminobutyric acid group was significantly higher than that in the control group and Berberis extract group (P<0.01). About SI challenged with ConA, there was no significant difference among all groups at 14 and 42 days (P>0.05), but at 28 days, the combined group and gamma aminobutyric acid group were significantly higher than the control group and Berberis extract group (P<0.05). In conclusion, gamma aminobutyric acid can be used as a substitute of antibiotic additives in the diet, and will not affect growth performance and immune function of broilers. Adding both Berberis extract and gamma aminobutyric acid in the diet will get the better effects.

Key words： Berberis extract; gamma aminobutyric acid; broilers; growth performance; antibody

Cite this article

ZHANG Guanghui, XIE Jinhui, CHEN Pengju . Effects of Dietary Berberis Extract and Gamma Aminobutyric Acid on Growth Performance and Immune Function of Broilers[J]. Chinese Journal of Animal Nutrition, 2011 , 23(11) : 1984 -1990 . DOI: 10.3969/j.issn.1006-267x.2011.11.020

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