This experiment was conducted to investigate the effects of a diet supplemented with yeast nucleotides on growth performance, antioxidant function and disease resistance of bluntnose black bream. Three hundred fish with an initial body weight of (31.46?0.07) g were randomly allotted to 2 groups (control group and nucleotide group) and each group included 3 replicates with 50 fish. The fish in the control group were fed a basal diet, and those in the nucleotide group were fed an experimental diet supplemented with 200 mg/kg yeast nucleotide (the total content of single nucleotides and oligonucleotides was 70%). After 56 days feeding, the growth, body and blood physiological and biochemical indices of fish were determined, and the cumulative mortality rate of fish was also be determined for Aeromonas hydrophila challenge test at the end of feeding experiment. The results showed as follows: the diet supplemented with 200 mg/kg yeast nucleotide significantly increased the specific growth rate and protein efficiency ratio (P<0.05), and significantly decreased the feed coefficient ratio (P<0.05), but had no significant effects on the feeding rate, hepatosomatic index, viscerasomatic index, condition factor and survival rate of bluntnose black bream (P>0.05). Compared with the control group, the plasma anti-superoxide anion level in the nucleotide group was significantly increased (P<0.05), but the alkaline phosphatase activity had no significant change (P>0.05). The diet supplemented with 200 mg/kg yeast nucleotide had no significant effects on the liver function, blood lipid and blood glucose indices of bluntnose black bream (P>0.05), but could significantly decrease the cumulative mortality rate after Aeromonas hydrophila challenge 96 to 168 h (P<0.05). It is concluded that the diet supplemented with 200 mg/kg yeast nucleotide can promote the growth, enhance the antioxidant function and disease resistance, but do not affect the liver function, blood lipid and blood glucose metabolism of bluntnose black bream.
ZHANG Yiping
,
LIU Bo
,
HUA Xunlu
,
SUN Mei
,
XIE Jun
,
SHI Jijun
. Effects of Yeast Nucleotide on Growth Performance, Antioxidant Function and Disease Resistance of Bluntnose Black Bream[J]. Chinese Journal of Animal Nutrition, 2012
, 24(3)
: 583
-590
.
DOI: 10.3969/j.issn.1006-267x.2012.03.028
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