Anti/Pro-oxidative Functions of Antioxidants and Their Mechanisms

  • CHEN Wei ,
  • LIN Yingcai ,
  • MA Xianyong ,
  • JIANG Zongyong
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  • Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Livestock and Poultry Breeding, The Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture, Guangdong Public Laboratory of Animal Breeding and Nutrition, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China

Received date: 2011-12-08

  Online published: 2012-03-30

Abstract

Under some severe pathological conditions induced by serious environment, bacteria or virus, the balance between anti-oxidation and oxidation was disturbed, which leaded to oxidative injury of cells and body, and had negative effects on animal health and production. Vitamin A, C, E and α-lipoic acid were commonly used as antioxidants in animal production. However, a growing body of evidence showed that these oxidants exerted anti-oxidative effects in a relatively low dose, whereas they caused pro-oxidative potential in body when used in a high dose. The pathway involved in the production of reactive oxygen species and the potential mechanism involved in anti/pro-oxidative effect are summarized in this review.

Cite this article

CHEN Wei , LIN Yingcai , MA Xianyong , JIANG Zongyong . Anti/Pro-oxidative Functions of Antioxidants and Their Mechanisms[J]. Chinese Journal of Animal Nutrition, 2012 , 24(4) : 595 -605 . DOI: 10.3969/j.issn.1006-267x.2012.04.002

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