REVIEW

Integrin: Regulation of Signal Transduction Pathways on Skeletal Muscle Growth and Development

  • LI Xinwei ,
  • ZHANG Yong
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  • College of Veterinary and Animal Science, Shenyang Agricultural University, Shenyang 110866, China

Received date: 2012-02-08

  Online published: 2012-07-05

Abstract

Integrins widely distribute on eukaryotic cell membrane, and are a class of α/β heterodimeric membrane receptor proteins, which can increase cell adhesion to extracellular matrix, mediate mechanical and chemical signals from the matrix, and regulate cell differentiation, migration, immune, adhesion and other biological functions through bio-directional signal transduction of membrane. This article reviewed the function and activation characteristics of integrin signal transduction pathways, and focused on the regulation of integrin and their signal transduction pathways on skeletal muscle growth and development.

Cite this article

LI Xinwei , ZHANG Yong . Integrin: Regulation of Signal Transduction Pathways on Skeletal Muscle Growth and Development[J]. Chinese Journal of Animal Nutrition, 2012 , 24(7) : 1201 -1206 . DOI: 10.3969/j.issn.1006-267x.2012.07.003

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