To identify the effects of dietary sorbic acid (SA) on growth performance, the villus morphology of small intestine, organ indexes, serum biochemical indexes, and related genes mRNA expression in weaner piglets, one hundred and eighty 28-day-old purebred Yorkshire weaner piglets were randomly allotted to four groups with three replicates per group and 15 piglets per pen (eight barrows and seven gilts). The groups received the same basal diet supplemented with 0 (control group), 0.050% (0.050% SA group), 0.125% (0.125% SA group), and 0.200% (0.200% SA group) SA, respectively. There was a pretrial period of 7 days followed by an experimental period of 42 days. The results showed as follows: 1) compared with the control group, adding 0.200% SA significantly increased body weight at 56 and 77 days of age and average daily gain during the whole period (P<0.05), but the villus morphology of small intestine and organ indexes were unchanged (P>0.05). 2) Serum contents of total protein, low density lipoprotein and insulin-like growth factor-Ⅰ (IGF-Ⅰ) in 0.200% SA group, and albumin and high density lipoprotein in 0.050% and 0.125% SA groups were significantly higher than those in control group (P<0.05). 3) Compared with the control group, supplemented with 0.200% SA in diets significantly down-regulated muscle peroxisome proliferator-activated receptor γ (PPARγ) mRNA expression level (P<0.05). These results indicate that the promoting effect of 0.200% SA on growth performance may be associated with the increased serum IGF-Ⅰ content regulated by PPAR system in weaner piglets.
GAO Ping
,
WANG Haifeng
,
FANG Xinling
,
SHU Gang
,
ZHU Xiaotong
,
WANG Songbo
,
WANG Lina
,
JIANG Qingyan
. Effects of Dietary Sorbic Acid on Growth Performance, Serum Biochemical Indexes and Related Genes mRNA Expression of Weaner Piglets[J]. Chinese Journal of Animal Nutrition, 2012
, (11)
: 2195
-2202
.
DOI: 10.3969/j.issn.1006-267x.2012.11.018
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