This experiment was conducted to study the effects of adding bamboo-carbon and bamboo vinegar to the diets contaminated by deoxynivalenol (DON) on growing performance, hematologic indexes, serum biochemical indexes and viscera indexes of weaner piglets. A total of 28 crossbred (Duroc譒andrace譒arge White) weaner piglets with an average body weight of (12.19?0.18) kg were randomly assigned to 4 groups with 7 replicates per group and 1 piglet in each replicate. The 4 groups were as follows: control group (a basal diet), DON group (the basal diet+DON), bamboo-carbon group (the basal diet+DON+2% bamboo-carbon) and bamboo vinegar group (the basal diet+DON+1% bamboo vinegar). The experimental period lasted for 37 d. The results showed as follows: 1) compared with the control group, average daily gain (ADG) in DON group was significantly decreased (P<0.05), and the ratio of feed to gain was increased significantly (P<0.05); compared with the DON group, ADG and average daily feed intake (ADFI) had a increasing trend (P>0.05), and the ratio of feed to gain in bamboo vinegar group had a decreasing trend (P>0.05). 2) On d 15 of the experiment, the red blood cell (RBC) count in DON group was significantly decreased compared with the control group (P<0.05), there was no significant difference in RBC count between bamboo-carbon group and control group (P>0.05), but that in bamboo vinegar group was significantly higher than that in control group and bamboo-carbon group (P<0.05); the hematocrit (HCT) in DON group and bamboo-carbon group was significantly decreased compared with the control group (P<0.05), and there was no significant difference between bamboo vinegar group and control group (P>0.05). There were no significant differences in hematologic indexes among DON group, bamboo-carbon group, bamboo vinegar group and control group on d 30 of the experiment (P>0.05). 3) There were no effects on serum contents of immunoglobulin G (IgG), immunoglobulin M (IgM) and glucose (GLU) and activities of lactate dehydrogenase (LDH) and glutamic-oxal(o)acetic transaminase (GOT) in the whole experimental period. On d 15 of the experiment, the activity of glutamic-pyruvic transaminase (GPT) in serum in DON group and bamboo vinegar group was significantly higher than that in the control group (P<0.05), but there were no significant differences between bamboo-carbon group and control group (P>0.05). On d 30 of the experiment, the serum content of total protein (TP) in DON group was significantly decreased compared with control group and bamboo vinegar group (P<0.05), but there was no significant difference among bamboo-carbon group, bamboo vinegar group and control group (P>0.05). On d 37 of the experiment, the serum content of urea nitrogen (UN) in DON group was significantly higher than that in control group and bamboo vinegar group (P<0.05), but there was no significant difference among bamboo-carbon group, bamboo vinegar group and control group (P>0.05). 4) There were no significant differences in the liver, pancreas, spleen, heart, gall bladder, thymus indexes between experiment group and control group (P>0.05), but the liver index in DON group had a increasing trend, but no significant difference (P>0.05). In conclusion,1)DON can reduce growth performance of weaner piglets, and the 1% bamboo vinegar added in the diets can reverse the weaner piglets from the injury of DON toxin. 2)The effects of diets contaminated by DON are more obvious in the early growing period than those in the later growing period, and the possible reason may be that the weaner piglets have certain tolerant ability to DON with the time increasing. 3)DON can result in the toxicity such as the decrease of blood cell count, the increase of GPT activity and UN content, and the decrease of TP content in serum. The 2% bamboo-carbon and 1% bamboo vinegar added in the diets can reverse the activity of GPT, the contents of UN and TP in serum to normal. It is concluded that the 2% bamboo-carbon and 1% bamboo vinegar can effectively adsorb DON toxin.