This experiment was designed to assess the apparent digestible energy and nutrient apparent digestibility of millet straw for meat rabbits. Forty-two 70 to 80 day-old meat rabbits with an average body weight of (1.29±0.12) kg were randomly allocated into 7 groups with 6 replicates per group. The experimental diets were prepared by substitution method, and millet straw from Zhangwu and Lingyuan regions of Liaoning province was substituted with basal diet at ratios of 20%, 15% and 10%, respectively. Digestion experiment was conducted by the method of total fecal collection, and both pre-trial and trial period lasted for 5 days. The results showed that the average contents of crude protein (CP), crude fiber (CF), neutral detergent fiber (NDF), acid detergent fiber (ADF), crude ash (Ash), calcium (Ca) and total phosphorus (P) in millet straw were 7.35%, 34.96%, 67.20%, 46.06%, 17.85%, 1.01% and 0.16%; and the average apparent digestibility of CP, CF, NDF, ADF, Ash, Ca and P were 81.98%, 18.70%, 8.83%, 17.82%, 22.23%, 68.92% and 25.03%, respectively. The apparent digestibility of ADF and Ca was significant difference between Zhangwu and Lingyuan regions (P＜0.05), however, the other nutrient apparent digestibility had no significant difference between Zhangwu and Lingyuan regions (P＞0.05). The average gross energy (GE) in millet straw was 16.39 MJ/k, the average apparent digestible energy (ADE)in millet straw from Zhangwu region was higher than that from Lingyuan region by 27.66% (P＞0.05). In conclusion, the apparent digestibility of GE, CF, NDF and ADF is lower, and the apparent digestibility of CP and Ca is higher in millet straw for meat rabbits.