Biological Characteristics and Functions of Early Growth Response-1

ZHU Taotao; ZHU Yujing; ZHANG Yong; SHAO Caimei

doi:10.3969/j.issn.1006-267x.2013.04.003

Chinese Journal of Animal Nutrition >

2013 , Vol. 25 >Issue 4: 685 - 691

DOI: https://doi.org/10.3969/j.issn.1006-267x.2013.04.003

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Biological Characteristics and Functions of Early Growth Response-1

ZHU Taotao ,
ZHU Yujing ,
ZHANG Yong ,
SHAO Caimei

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1. College of Veterinary and Animal Science, Shenyang Agricultural University, Shenyang 110866, China;
2. Liaoning Wellhope Agri-Tech Co., Ltd., Shenyang 110164, China

Received date: 2012-10-08

Online published: 2013-03-25

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Abstract

Early growth response-1 (Egr-1) can participate in the regulation of cellular growth and differentiation, as well as cell growth control process by regulating a series of genes which are associated with cellular growth, proliferation and differentiation in cell cycle, and it also promote cell proliferation and tissue repair. Egr-1 can be influenced by a diversity of upstream molecules and combine to the specific sequences of the promoter region in downstream molecules. Egr-1 gene expression is induced instantly when suffered extensive stimulus, which can lead to different functions. The impacts of Egr-1 on animal growth, reproduction and immunity were reviewed in this article.

Key words： early growth response-1; biological characteristics; growth and development; reproduction; immunity

Cite this article

ZHU Taotao , ZHU Yujing , ZHANG Yong , SHAO Caimei . Biological Characteristics and Functions of Early Growth Response-1[J]. Chinese Journal of Animal Nutrition, 2013 , 25(4) : 685 -691 . DOI: 10.3969/j.issn.1006-267x.2013.04.003

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