Effects of Aflatoxin-Detoxifizyme on Growth Performance and Hepatic Biochemical Indexes of Weaner Piglets Fed Diets Containing Aflatoxin B1

YU Huimin; LIANG Chenchong; CHEN Baojiang; CAI Huiyi; WANG Yong; LIU Shijie

doi:10.3969/j.issn.1006-267x.2013.04.018

2013 , Vol. 25 >Issue 4: 805 - 811

DOI: https://doi.org/10.3969/j.issn.1006-267x.2013.04.018

Feed Security

Effects of Aflatoxin-Detoxifizyme on Growth Performance and Hepatic Biochemical Indexes of Weaner Piglets Fed Diets Containing Aflatoxin B₁

YU Huimin ,
LIANG Chenchong ,
CHEN Baojiang ,
CAI Huiyi ,
WANG Yong ,
LIU Shijie

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1. Feed Research Institute Chinese Academy of Agricultural Sciences, Beijing 100081, China;
2. College of Animal Science and Technology, Agricultural University of Hebei, Baoding 071001, China

Received date: 2012-10-17

Online published: 2013-03-25

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Abstract

This experiment was conducted to evaluate the effects of aflatoxin-detoxifizyme (ADTZ) on the growth performance and hepatic biochemical indexes of weaner piglets fed diets containing aflatoxin B₁ (AFB₁), and investigated the application effect. A total of 108 piglets, whose age difference was not more than three days, and with the same genetic background, body weight, and consistent sex ratio, were randomly divided into 3 groups: control group (basal diet), AFB₁ group (basal diet+0.1 mg/kg AFB₁) and ADTZ group (basal diet+0.1 mg/kg AFB₁+0.2% ADTZ), and with 6 replicates per group. The experiment lasted for 30 days. The results showed as follows: 1) compared with control group, in AFB₁ group, average daily gain (ADG) and average daily feed intake (ADFI) were decreased (P>0.05), and feed/gain was increased (P>0.05); the activities of glutathione reductase, catalase and succinic dehydrogenase were significantly decreased (P<0.05), and the activities of superoxide dismutase, glutathione peroxidase and choline esterase were decreased (P>0.05), while alkaline phosphatase activity and MDA content were increased (P>0.05); 2) compared with control group, in ADTZ group, ADG and ADFI were increased (P>0.05), and feed/gain was increased (P>0.05); biochemical indexes were returned to normal levels. Adding AFB₁ to the basal diet can lead to a decline in growth performance and hepatic physiological functions; adding ADTZ can effectively reduce the harm of AFB₁ on weaner piglets, improve growth performance and protect the hepatic physiological functions.

Key words： weaner piglets; aflatoxin-detoxifizyme; aflatoxin B₁; growth performance; biochemical indexes

Cite this article

YU Huimin , LIANG Chenchong , CHEN Baojiang , CAI Huiyi , WANG Yong , LIU Shijie . Effects of Aflatoxin-Detoxifizyme on Growth Performance and Hepatic Biochemical Indexes of Weaner Piglets Fed Diets Containing Aflatoxin B₁[J]. Chinese Journal of Animal Nutrition, 2013 , 25(4) : 805 -811 . DOI: 10.3969/j.issn.1006-267x.2013.04.018

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