This experiment was conducted to investigate the effects of raffinose on growth performance, nutrient digestion and metabolism, intestinal microflora and immune function of minks. Fifty healthy male minks were randomly divided into 5 groups, and each group had 10 replicates and each replicate had 1 mink. The minks in control group was fed a basal diet, and the minks in test groups Ⅰ, Ⅱ, Ⅲ and Ⅳ were fed the experimental diets supplemented with 0.5, 1.0, 2.0 and 4.0g/kg raffinose, respectively. The experiment lasted for 45 days. The results showed as follows: raffinose supplementation had no significant effects on average daily feed intake (ADFI), average daily gain (ADG) and feed/gain (P>0.05), but there had a trend to improve ADFI and ADG. Raffinose supplementation had no significant effects on indices of nutrient digestion and metabolism, and organ (liver, spleen and kidney) indices (P>0.05). The number of intestinal Escherichia coli in the test groups was lower than that in the control group, but the difference was not significant (P>0.05). The number of intestinal Lactobacillus was not significantly affected by raffinose supplementation (P>0.05). The supplementation of 0.5 g/kg raffinose improved the number of intestinal Bifidobacterium bifidum (P<0.05). No significant differences were found in the contents of total protein, albumin, globulin, complement 3, complement 4, immunoglobulin M, total thyroxine (TT₄) and total triiodothyronine (TT₃) in serum among all groups (P>0.05). Compared with the control group, serum immunoglobulin A content in the group supplemented with 0.5 g/kg raffinose was significantly increased (P<0.05), while serum immunoglobulin A content in the group supplemented with 2.0 g/kg raffinose was significantly decreased (P<0.05). Considering above all indices, the optimal level of raffinose in diets for minks is 0.5 g/kg.