Effects of Nicotinic Acid on Lipid Metabolism and Meat Quality and Its Mechanisms in Ruminants

YANG Zhuqing; QU Mingren; ZHAO Xianghui; OUYANG Kehui; YANG Yan

doi:10.3969/j.issn.1006-267x.2013.06.004

Chinese Journal of Animal Nutrition >

2013 , Vol. 25 >Issue 6: 1150 - 1157

DOI: https://doi.org/10.3969/j.issn.1006-267x.2013.06.004

Review

Effects of Nicotinic Acid on Lipid Metabolism and Meat Quality and Its Mechanisms in Ruminants

YANG Zhuqing ,
QU Mingren ,
ZHAO Xianghui ,
OUYANG Kehui ,
YANG Yan

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College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China

Received date: 2013-01-07

Online published: 2013-05-15

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Abstract

Nicotinic acid as a pre-product of NAD⁺ and NADP⁺ participates in many biochemical metabolisms such as lipid metabolism, tissue's oxidation and respiratory functions as well as glycolysis. It is also very important for fatty acid synthesis from acetic acid in ruminants. Nicotinic acid had been used as a lipid lowering agent for a long time, with special and all-round lipid modulation, which could inhibit adipocyte triglyeride (TG) decomposition and reduce serum free fatty acid level by GPR109A, and could inhibit the hepatic production of TG and very low density lipoprotein by diacylglycerol acyltransferase 2 (DGAT2), speeding up the degradation of apolipoprotein B. Therefore, nicotinic acid plays important roles in lipid metabolism and fat deposition in ruminants, and can improve the meat and milk quality or growth performance. In this paper, we summarized some effects of nicotinic acid in diets on lipid metabolism and meat quality and its mechanisms in ruminants, which might provide some useful information for production and practice.

Key words： nicotinic acid; ruminants; lipid metabolism; nutrition; meat quality; fat disposition

Cite this article

YANG Zhuqing , QU Mingren , ZHAO Xianghui , OUYANG Kehui , YANG Yan . Effects of Nicotinic Acid on Lipid Metabolism and Meat Quality and Its Mechanisms in Ruminants[J]. Chinese Journal of Animal Nutrition, 2013 , 25(6) : 1150 -1157 . DOI: 10.3969/j.issn.1006-267x.2013.06.004

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