Butafosfan Solutions：Effects on Growth Performance and Immune Function of Broilers

ZHANG Shizhong; WANG Quanxi; WANG Changkang; WU Nanyang; JIANG Bin

doi:10.3969/j.issn.1006-267x.2013.09.025

Chinese Journal of Animal Nutrition >

2013 , Vol. 25 >Issue 9: 2111 - 2117

DOI: https://doi.org/10.3969/j.issn.1006-267x.2013.09.025

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Butafosfan Solutions：Effects on Growth Performance and Immune Function of Broilers

ZHANG Shizhong ,
WANG Quanxi ,
WANG Changkang ,
WU Nanyang ,
JIANG Bin

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1. Institute of Anima Science and Veterinary, Fujian Academy of Agricultural Sciences, Fuzhou 350001, China;
2. College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China

Received date: 2013-05-15

Online published: 2013-08-18

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Abstract

To study the effects of butafosfan solution on growth performance and immune function of broilers, a total of 180 one-day-old healthy yellow-feathered broilers were randomly divided into 3 groups with 6 replicates in each group and 10 broilers in each replicate. Control group (groupⅠ) was injected with saline solution, group Ⅱ was injected with domestic butafosfan solution, and group Ⅲ was injected with imported butafosfan solution. Experimental injection was carried out for three times, the first injection of 0.2 mL was at 1 day of age, the second injection of 0.5 mL was at 21 days of age, and the third injection of 1.0 mL was at 49 days of age. The experiment lasted for 56 days. The results showed as follows: 1) at 56 days of age, the average daily feed intake of groups Ⅱ and Ⅲwas significantly higher than that of group Ⅰ (P<0.05). The average daily gain of group Ⅱ was significantly higher compared with group Ⅰ (P<0.05), and group Ⅲ was significantly higher than group Ⅰ (P<0.01). However, the feed to gain ratio was not significantly different among the three groups (P>0.05). Disease incidence and mortality rate of groups Ⅱ and Ⅲ were significantly lower than those of group Ⅰ(P<0.01 and P<0.05). 2)At 28 and 56 days of age, the antibody level of Newcastle disease attenuated vaccine (clone 30) in serum of groups Ⅱ and Ⅲ was significantly higher than that of group Ⅰ (P<0.01), and there was no significant difference between group Ⅱ and group Ⅲ (P>0.05). But only the antibody level of H₅ subtype avian influenza of group Ⅲ was significantly higher than that of group Ⅰ (P<0.01), and there was no significant difference between group Ⅰ and group Ⅱ (P>0.05). Serum interleukin (IL-2) content of group Ⅲ was significantly higher than that of group Ⅰ (P<0.01 or P<0.05), but there was no significant difference between group Ⅰ and group Ⅱ (P>0.05), and there was no significant difference in serum IL-6 content among the three groups (P>0.05). The indexes of thymus, spleen and bursal of Fabricius of group Ⅲ were significantly higher than those of group Ⅰ at 56 days of age (P<0.05), thymus index was significantly higher than that of group Ⅱ (P<0.05), but there were no significant differences in the indexes of spleen and bursal of Fabricius compared with group Ⅱ (P>0.05). In conclusion, butafosfan solution can increase the average daily feed intake and the average daily gain of the broilers, and reduce the disease incidence and mortality rate, but can not affect feed to gain ratio. It can also promote the immune function and development of immune organs. The effects of imported butafosfan solution are better than those of domestic butafosfan solution.

Key words： butafosfan; growth performance; immune function

Cite this article

ZHANG Shizhong , WANG Quanxi , WANG Changkang , WU Nanyang , JIANG Bin . Butafosfan Solutions：Effects on Growth Performance and Immune Function of Broilers[J]. Chinese Journal of Animal Nutrition, 2013 , 25(9) : 2111 -2117 . DOI: 10.3969/j.issn.1006-267x.2013.09.025

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