Review

Taurine Transporter:Regulation Mechanism and Significance in Animal Nutrition Studies

  • ZHANG Xiaolong ,
  • DENG Huan ,
  • CHEN Cheng ,
  • ZHANG Suyun ,
  • TANG Zhiru
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  • 1. Biological Feed and Molecular Nutrition Laboratory, Southwest University, Chongqing 400715, China;
    2. College of Life Sciences, Guizhou University, Guiyang 550025, China

Received date: 2013-04-23

  Online published: 2013-09-16

Abstract

Taurine (Tau) is the most abundant free amino acid with a wide range of biological effects on excitable tissue cells, and it is mainly transported by taurine transporter (TAUT) into the membrane. TAUT is regulated by many factors, such as p53, sp1, c-Jun, Wilms tumor suppressor gene 1 (WT1), tonicity-responsive element (TonE), nuclear factor-κB (NF-κB), antioxidant responsive element (ARE), heat shock transcription factor 1 (HSF1) and protein kinase C (PKC), etc. This article reviewed the TAUT's type and structure, regulation mechanism in the transcriptional and post-transcriptional level, and the study significance of regulation mechanism in animal nutrition which would be a valuable reference for the application of Tau in the breeding industry.

Cite this article

ZHANG Xiaolong , DENG Huan , CHEN Cheng , ZHANG Suyun , TANG Zhiru . Taurine Transporter:Regulation Mechanism and Significance in Animal Nutrition Studies[J]. Chinese Journal of Animal Nutrition, 2013 , 25(10) : 2222 -2230 . DOI: 10.3969/j.issn.1006-267x.2013.10.005

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