Effects of Whey Powder on Growth Performance, Antioxidant and Immune Functions of Weanling Laboratory Rabbits

LYU Jianmin; CAI Zhaowei; CAI Yueqin; XU Jianqin; ZHU Keyan

doi:10.3969/j.issn.1006-267x.2013.12.023

Chinese Journal of Animal Nutrition >

2013 , Vol. 25 >Issue 12: 2951 - 2957

DOI: https://doi.org/10.3969/j.issn.1006-267x.2013.12.023

Feed Science and Technology

Effects of Whey Powder on Growth Performance, Antioxidant and Immune Functions of Weanling Laboratory Rabbits

LYU Jianmin ,
CAI Zhaowei ,
CAI Yueqin ,
XU Jianqin ,
ZHU Keyan

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Laboratory Animal Research Center, Zhejiang Chinese Medical University, Hangzhou 310053, China

Received date: 2013-06-03

Online published: 2013-11-19

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Abstract

This experiment was conducted to investigate the effects of whey power on growth performance, antioxidant and immune functions of weanling laboratory rabbits. Using a single factor design, a total of 48 weanling laboratory rabbits (40-day-old) with an average initial body weight of (1 095±75) g were randomly divided into 4 groups (with 12 replicates per group and 1 rabbit per replicate) and fed the experimental diets with whey powder supplemental levels at 0, 2%, 5% and 10%, respectively. Four experimental diets had approximately similar contents of digestible energy (9.33 to 9.35 MJ/kg), crude protein (17.10% to 17.20%) and crude fibre (15.00% to 15.10%). The whole trail lasted for 35 days (7 days of pretrial plus 28 days of formal trail), and the growth performance was measured during the formal trial, the antioxidant and immune indices were determined when the trial was finished. The results showed as follows: 1) supplying 5% or 10% whey powder extremely significantly decreased the feed /gain (F/G) (P<0.01), and significantly increased the average daily gain (ADG) of laboratory rabbits (P<0.05). The diarrhea and mortality rates were all 0 at 5% and 10% whey powder supplemental levels. 2) Supplying 2% whey powder significantly increased the serum activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) (P<0.05 or P<0.01), and the activities of serum SOD and GSH-Px were extremely significantly increased at 5% whey powder supplemental level (P<0.01). However, the serum maleic dialdehyde (MDA) content was significantly reduced at 10% whey powder supplemental level (P<0.05). 3) The contents of serum immunoglobulin A (IgA) and immunoglobulin G (IgG), as well as the thymus index were significantly increased at 5% whey powder supplemental level (P<0.05), and the serum IgA and IgG contents were extremely significantly increased at 10% whey powder supplemental level (P<0.01). It is concluded that whey powder can decrease the diarrhea and mortality rates, improve the growth performance, and enhance the antioxidant and immune functions of weanling laboratory rabbits. The optimal supplemental level of whey powder in the diet of weanling laboratory rabbits is 5%.

Key words： laboratory rabbit; growth performance; diarrhea rate; mortality rate; antioxidant function; immune function

Cite this article

LYU Jianmin , CAI Zhaowei , CAI Yueqin , XU Jianqin , ZHU Keyan . Effects of Whey Powder on Growth Performance, Antioxidant and Immune Functions of Weanling Laboratory Rabbits[J]. Chinese Journal of Animal Nutrition, 2013 , 25(12) : 2951 -2957 . DOI: 10.3969/j.issn.1006-267x.2013.12.023

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