This experiment was carried out to evaluate the nutritional values of sorghum and wheat for growing Rex rabbits by feeding and digestion trials. A total of 24 growing Rex rabbits with the age about 60 days and an average body weight of (1.68±0.23) kg were randomly divided into 4 groups (6 replicates per group and 1 rabbit per replicate). The rabbits in the 4 groups were fed a basal diet, a sorghum diet (85% basal diet＋15% sorghum), a wheat diet (85% basal diet＋15% wheat) and a corn diet (85% basal diet＋15% corn), respectively. Total fecal collection method was applied to determine the apparent digestibility of gross energy (GE), dry matter (DM), crude protein (CP), crude fiber (CF), neutral detergent fiber (NDF), acid detergent fiber (ADF), acid detergent lignin (ADL), ether extract (EE), crude ash (Ash), calcium (Ca), phosphorus (P) and nitrogen free extract (NFE) in sorghum, wheat and corn for growing Rex rabbits. Both pre-trial and trial periods lasted for 5 days. The results showed as follows: the apparent digestibility of GE, DM, CP, CF, NDF, ADF, ADL, EE, Ash, Ca, P and NFE in sorghum and wheat for growing Rex rabbits were 68.61%, 68.83%, 80.45%, 30.90%, 39.24%, 24.99%, 0.64%, 83.81%, 54.06%, 48.43%, 19.86%, 79.18% and 68.63%, 69.02%, 80.33%, 31.23%, 39.84%, 26.67%, 0.65%, 83.08%, 57.05%, 55.86%, 21.26%, 79.29%, respectively. The apparent digestibility of nutrients in sorghum and wheat were not significantly different compared with corn (P>0.05). The results indicate that the nutritional values of sorghum and wheat are similar with corn for growing Rex rabbits, and it is feasible that sorghum and wheat can replace the corn, but the replacement ratio need to be controlled because of the sorghum and wheat containing anti-nutritional factors. There are certain differences in nutrient apparent digestibility between sorghum and wheat for growing Rex rabbits, and the nutritional value of wheat is slightly higher than that of sorghum based on comprehensive consideration.