Effects of Vitamin D Supplemental Level on Growth Performance, Calcium and Phosphorus Metabolism, Blood Indices and Antioxidant Function of Growing Rex Rabbits

LI Wanjia; LI Fuchang; ZHU Xiaoqiang; FU Zhaohui; ZHANG Caixia

doi:10.3969/j.issn.1006-267x.2014.02.014

2014 , Vol. 26 >Issue 2: 389 - 396

DOI: https://doi.org/10.3969/j.issn.1006-267x.2014.02.014

Special Economic Animal Nutrition

Effects of Vitamin D Supplemental Level on Growth Performance, Calcium and Phosphorus Metabolism, Blood Indices and Antioxidant Function of Growing Rex Rabbits

LI Wanjia ,
LI Fuchang ,
ZHU Xiaoqiang ,
FU Zhaohui ,
ZHANG Caixia

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College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China

Received date: 2013-09-05

Online published: 2014-01-27

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Abstract

This experiment was conducted to study the effects of vitamin D supplemental level on growth performance, calcium (Ca) and phosphorus (P) metabolism, blood indices and antioxidant function of growing Rex rabbits. Two hundred 3-month-old Rex rabbits with an average body weight of (1.45±0.03) kg were randomly assigned to 5 groups with 40 replicates in each group and each replicate contained 1 rabbit. Rabbits in the 5 groups were fed experimental diets with the vitamin D supplemental levels of 0 (control group), 500, 1 000, 2 000 and 4 000 IU/kg, respectively. There was a pretrial period of 7 days followed by an experimental period of 53 days. The results showed as follows: vitamin D supplemental level did not significantly affect the average daily intake (ADI), average daily gain (ADG) and feed/gain (F/G) (P>0.05), and the highest ADG was found in 2 000 IU/kg group. Vitamin D supplemental level did not significantly affect serum Ca and P contents, fecal P content and shin P content (P>0.05). The fecal Ca content in 2 000 IU/kg group was significantly lower than that in 0, 500 and 4 000 IU/kg groups (P<0.05), and shin Ca content in 2 000 IU/kg group was significantly higher than that in 0, 500 and 1 000 IU/kg groups (P<0.01). Vitamin D supplemental level did not significantly affect the apparent digestibility of Ca and P (P>0.05), but with the increase of vitamin D supplemental level, the apparent digestibility of Ca and P showed a trend of first rise and then decrease, and the highest value was found in 2 000 IU/kg group. Vitamin D supplemental level did not significantly affect serum alkaline phosphatase (ALP) activity and the contents of triglyceride (TG), cholesterol (CHO), high density lipoprotein cholestorol (HDL-C), low density lipoprotein cholestorol (LDL-C) and parathyroid hormone (PTH) (P>0.05). Serum total protein (TP), albumin (ALB), calcitonin (CT) and vitamin D₃ contents in 2 000 IU/kg group were the highest and significantly higher than those in the control group (P<0.05). Serum glutathione peroxidase (GSH-Px) activity in 2 000 IU/kg group was significantly higher than that in control group and 500 IU/kg group (P<0.01), serum total superoxide dismutase (T-SOD) activity in 1 000, 2 000 and 4 000 IU/kg groups was significantly higher than that in control group and 500 IU/kg group (P<0.01), liver GSH-Px activity in 2 000 IU/kg group was significantly higher than that in other 4 groups (P<0.01), and liver T-SOD activity in 2 000 IU/kg group was significantly higher than that in control group (P<0.05). Vitamin D supplemental level did not significantly affect serum and liver malondialdehyde (MDA) content and liver total antioxidant capability (T-AOC) (P>0.05). Considering all measured indices of this experiment, the appropriate vitamin D supplemental level in the diet of growing Rex rabbits is 2 000 IU/kg.

Key words： vitamin D; growing Rex rabbit; growth performance; calcium and phosphorus metabolism; blood indices; antioxidant function

Cite this article

LI Wanjia , LI Fuchang , ZHU Xiaoqiang , FU Zhaohui , ZHANG Caixia . Effects of Vitamin D Supplemental Level on Growth Performance, Calcium and Phosphorus Metabolism, Blood Indices and Antioxidant Function of Growing Rex Rabbits[J]. Chinese Journal of Animal Nutrition, 2014 , 26(2) : 389 -396 . DOI: 10.3969/j.issn.1006-267x.2014.02.014

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