Effects of Antimicrobial Peptide and Curcumin on Growth Performance and Immune Function of Broilers Aged from 1 to 21 Days

PENG Xiang; SUN Quanyou; LI Jie; XU Bin; WEI Fengxian; WANG Linyi; BAI Jie; LU Min; LI Shaoyu

doi:10.3969/j.issn.1006-267x.2014.02.024

2014 , Vol. 26 >Issue 2: 474 - 481

DOI: https://doi.org/10.3969/j.issn.1006-267x.2014.02.024

Feed Science and Technology

Effects of Antimicrobial Peptide and Curcumin on Growth Performance and Immune Function of Broilers Aged from 1 to 21 Days

PENG Xiang ,
SUN Quanyou ,
LI Jie ,
XU Bin ,
WEI Fengxian ,
WANG Linyi ,
BAI Jie ,
LU Min ,
LI Shaoyu

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1. College of Livestock Husbandry and Veterinary Engineering, Henan Agricultural University, Zhengzhou 450002, China;
2. Institute of Animal Science, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China

Received date: 2013-08-23

Online published: 2014-01-27

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Abstract

This experiment was conducted to study the effects of antimicrobial peptide and curcumin on growth performance, immune organ indices, lymphocyte transformation rates and serum immunoglobulin contents of broilers aged from 1 to 21 days. A total of 360 one-day-old Arbor Acres (AA) broilers were randomly divided into 5 treatments with 6 replicates per treatment and 12 broilers per replicate. Broilers in the control group were fed a basal diet, and others in antibiotic group, antimicrobial peptide group, curcumin group and antimicrobial peptide+curcumin group were fed the basal diets supplemented with 35 g/t antibiotic, 200 g/t antimicrobial peptide, 200 g/t curcumin and 200 g/t antimicrobial peptide +200 g/t curcumin. The experiment lasted for 21 days.The results showed as follows: 1) the average daily feed intake in antibiotic group, curcumin group and antimicrobial peptide+curcumin group was significantly higher than that in control group (P<0.01), and the average daily gain in antibiotic group, antimicrobial peptide group, curcumin group and antimicrobial peptide+curcumin group was significantly higher than that in control group (P<0.01), while the ratio of feed to gain in antimicrobial peptide group was significantly lower than that in control group (P<0.01). 2) The immune organ indices in antimicrobial peptide+curcumin group were significantly higher than those in control group (P<0.01), the spleen index in antimicrobial peptide group was significantly higher than that in control group (P<0.01), and the bursa of Fabricius index in curcumin group were significantly higher than that in control group (P<0.01). 3) The transformation rates of T and B lymphocyte in antimicrobial peptide group, curcumin group and antimicrobial peptide+curcumin group were significantly higher than those in control group (P<0.01). 4) The serum immunoglobulin G content in antimicrobial peptide group and antimicrobial peptide+curcumin group was significantly higher than that in control group (P<0.01). It is concluded that the addition of antimicrobial peptide and curcumin alone or combined in the diet can improve the growth performance and immune function of broilers. The combination effect is better than alone effect, which is indicate that the combination of antimicrobial peptide and curcumin has a synergistic reaction.

Key words： antimicrobial peptides; curcumin; broilers; growth performance; immune function

Cite this article

PENG Xiang , SUN Quanyou , LI Jie , XU Bin , WEI Fengxian , WANG Linyi , BAI Jie , LU Min , LI Shaoyu . Effects of Antimicrobial Peptide and Curcumin on Growth Performance and Immune Function of Broilers Aged from 1 to 21 Days[J]. Chinese Journal of Animal Nutrition, 2014 , 26(2) : 474 -481 . DOI: 10.3969/j.issn.1006-267x.2014.02.024

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