Review

Research Advances on the Effects of Free Gossypol on Egg Quality and Its Removal Methord

  • WANG Xiaocui ,
  • WU Shugeng ,
  • ZHANG Haijun ,
  • QI Guanghai ,
  • LI Jie
Expand
  • 1. National Engineering Research Center of Biological Feed, Key Laboratory of Feed Biotechnology of Ministry of Agricultural, Feed Research Institute Chinese Academy of Agricultural Science, Beijing 100081, China;
    2. Institute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, China

Received date: 2013-10-28

  Online published: 2014-03-04

Abstract

The residue of cottonseed after oil extraction processing known as cottonseed meal is a fairly good source of protein and metabolizable energy. But free gossypol (FG) seriously affects the acceptability of the egg, and even further endangers human health, as well as seriously lowers the application of cottonseed meal in layer diets. In this paper, the structure and toxicity of gossypol, and the effects of FG on egg quality and its removal method were summarized.

Cite this article

WANG Xiaocui , WU Shugeng , ZHANG Haijun , QI Guanghai , LI Jie . Research Advances on the Effects of Free Gossypol on Egg Quality and Its Removal Methord[J]. Chinese Journal of Animal Nutrition, 2014 , 26(3) : 571 -577 . DOI: 10.3969/j.issn.1006-267x.2014.03.003

References

[1] LIU J G, STIPANOVIC R D, BELL A A, et al.Stereoselective coupling of hemigossypol to form (+)-gossypol in moco cotton is mediated by a dirigent protein[J].Phytochemistry, 2008, 69(18):3038-3042.  

[2] 丁耿芝, 邹晓庭.棉粕的营养及其在蛋鸡上应用的研究进展[J].饲料博览, 2010(12):14-16.

[3] 李佳, 袁洪水, 朱宝成.棉籽饼中棉酚降解菌株的分离及脱毒效果初探[J].科技传播, 2010(14):85, 91.

[4] MCCAUGHEY K M, DEPETERS E J, ROBINSON P H, et al.Impact of feeding whole upland cottonseed, with or without cracked pima cottonseed with increasing addition of iron sulfate, on productivity and plasma gossypol of lactating dairy cattle[J].Animal Feed Science and Technology, 2005, 122(3):241-256.

[5] 高玉时, 唐梦君, 陆俊贤, 等.高棉籽粕饲粮对蛋鸡生产性能及蛋品质的影响研究[J].中国家禽, 2012, 34(6):16-19.

[6] 吕云峰, 王修启, 赵青余, 等.棉酚在饲料中安全限量及畜产品中残留研究进展[J].中国农学通报, 2010, 26(24):1-5.

[7] 曾秋凤, 柏鹏.棉酚在肉禽体内的毒性和残留及其营养对策的研究进展[J].动物营养学报, 2013, 25(5):917-922.

[8] 沈峥.棉酚与"橡皮蛋"[J].化学教学, 2009(12):50-52.

[9] ADAMS R, GEISSMAN T A, MORRIS R C.Structure of gossypol.Ⅹ Ⅵ.Reduction products of gossypolone tetra methyl ether and gossypolonic acid tetramethyl ether[J].Journal of the American Chemical Society, 1938, 60:2967-2970.

[10] EDWARDS J D, Jr.Total synthesis of gossypol[J].Journal of the American Chemistry Society, 1958, 80(14):3798-3799.

[11] VANDER JAGT D L, DECK L M, ROYER R E.Gossypol prototype of inhibitors targeted to dinucleotide folds[J].Current Medicinal Chemistry, 2000, 7(4):479-498.  

[12] NAKADATE T, JENG A Y, BLUMBERG P M.Comparsion of protein kinase C functional assays to clarify mechanisms of inhibitor action[J].Biochemical Pharmacology, 1988, 37(8):1541-1545.  

[13] ALI I N, FAKHRILDIN M B M R, AL-OBAIDI S A R.Effect of aqueous and alcoholic extracts of cottonseed on some parameters of sperms and reproductive performance of albino mice[J].Journal of Al-Nahrain University, 2010, 13(4):151-158.

[14] RANDEL R D, CHASE C C, Jr, WYSE S J.Effects of gossypol and cottonseed products on reproduction of mammals[J].Journal of Animal Science, 1992, 70(5):1628-1638.

[15] DODOU K.Investigations of gossypol:past and present developments[J].Expert Opinion on Investigational Drugs, 2005, 14(11):1419-1434.  

[16] ROBINSON P H, GETACHEW G, DE PETERS E J, et al.Influence of variety and storage for up to 22 days on nutrient composition and gossypol level of pima cottonseed (Gossypium spp.)[J].Animal Feed Science and Technology, 2001, 91(3/4):149-156.

[17] NARAIN R, LYMAN C M, DEYOE C W, et al.Paper electrophoresis and albumin/globulin ratios of the serum of normal chickens and chickens fed free gossypol in diet[J].Poultry Science, 1961, 40(1):21-25.  

[18] WALDEOUP P W, GOODNER T O.Tolerance levels of free gossypol in layer diets as influenced by iron:gossypol ratios[J].Poultry Science, 1973, 52(1):20-28.  

[19] SURYWANSHI S N, BHANDARKAR A G, BHAGWAT S S.Pathological investigations of acute cottonseed cake toxicity in rabbit and chicken[J].Livestock Adviser, 1993, 18(1):30-32.

[20] 张爱婷, 朱巧明, 顾林英, 等.膨化棉籽粕对蛋鸡生产性能、蛋品质及血清生化指标的影响[J].动物营养学报, 2012, 24(6):1143-1149.

[21] PANIGRAHI S, HAMMONDS T W.Egg discolouration effects of including screw-press cottonseed meal in laying hen diets and their prevention[J].British Poultry Science, 1990, 31(1):107-120.  

[22] 冷青文, 申红, 王志祥.未脱毒棉籽饼对蛋鸡生产性能及其生殖器官的影响[J].畜禽业, 1999(11):34-35.

[23] 陈连颐, 唐梦君, 陆俊贤, 等.棉籽粕对海赛克斯蛋鸡生产性能及蛋品质的影响[J].中国家禽, 2012, 34(24):29-32.

[24] 方琴音.饲粮不同棉籽饼用量对商品蛋鸡生产性能、蛋品质、血液生化指标的影响研究[D].硕士学位论文.雅安:四川农业大学, 2004.

[25] STEPHENSON E L, SMITH R M.The storage quality of eggs produced by hens fed screw pressed cottonseed meal[J].Poultry Science, 1952, 31(1):98-100.  

[26] BERRY J G, NEWELL G W, HOLDER D P, et al.The effect of cottonseed products and selected feed additives on egg yolk discoloration[J].Poultry Science, 1968, 47(3):783-794.  

[27] PROCTOR J, O'NEILL H J, REILICH H G, et al.Physiological evaluation of solvent-treated cottonseed meals in rations for laying hens[J].Journal of the American Oil Chemists' Society, 1968, 45(5):393-396.  

[28] REILICH H G, O'NEILL H J, LEVI R S, et al.Chemical inactivation of cyclopropenoid fatty acids in cottonseed meals and their physiological evaluation[J].Journal of the American Oil Chemists' Society, 1969, 46(6):305-311.  

[29] FLETCHER J L, BARRENTINE B F, DREESEN L J, et al.The use of ferrous sulfate to inactivate gossypol in diets of laying hens[J].Poultry Science, 1953, 32(4):740-742.  

[30] LORDELO M M, CALHOUN M C, DALE N M, et al.Relative toxicity of gossypol enantiomers in laying and broiler breeder hens[J].Poultry Science, 2007, 86(3):582-590.  

[31] GILANI A, KERMANSHAHI H, GOLIAN A, et al.Impact of sodium bentonite addition to the diets containing cottonseed meal on productive traits of HY-line W-36 hens[J].The Journal of Animal and Plant Sciences, 2013, 23(2):411-415.

[32] PANIGRAHI S, PLUMB V E, MACHIN D H.Effects of dietary cottonseed meal, with and without iron treatment, on laying hens[J].British Poultry Science, 1989, 30(3):641-651.  

[33] PANIGRAHI S, MORRIS T R.Effects of dietary cottonseed meal and iron-treated cottonseed meal in different laying hen genotypes[J].British Poultry Science, 1991, 32(1):167-184.  

[34] PANIGRAHI S.Effects of treating cottonseed meal with a solution of ferrous sulphate on laying hen performance and discolorations in eggs[J].Animal Feed Science and Technology, 1992, 38(2/3):89-103.

[35] REID B L, GALAVIZ-MORENO S, MAIORINO P M.A comparison of glandless and regular cottonseed meals for laying hens[J].Poultry Science, 1984, 63(9):1803-1809.  

[36] SHAH F H, SHAH W F, YASIN M, et al.Detoxiflcation of commercially produced cottonseed meal[J].Pakistan Journal of Scientific and Industrial Research, 1986, 29(5):380-382.

[37] MAYORGA H, GONZLEZ J, MENCH J F, et al.Preparation of a low free gossypol cottonseed flour by dry and continuous processing[J].Journal of Food Science, 1975, 40(6):1270-1274.  

[38] NAGALAKSHMI D, SASTRY V R B, AGRAWAL D K.Detoxiflcation of undecorticated cottonseed meal by various physical and chemical methods[J].Animal Nutrition and Feed Technology, 2002, 2(2):117-126.

[39] GAMBOA D A, CALHOUN M C, KUHLMANN S W, et al.Tissue distribution of gossypol enantiomers in broilers fed various cottonseed meals[J].Poultry Science, 2001, 80(7):920-925.  

[40] PANIGRAHI S, PLUMB V E.Effects on dietary phosphorus of treating cottonseed meal with crystalline ferrous sulphate for the prevention of brown yolk discoloration[J].British Poultry Science, 1996, 37(2):403-411.  

[41] HILL C H, MATRONE G.Studies on copper and iron deficiencies in growing chickens[J].The Journal of Nutrition, 1961, 73(4):425-431.

[42] MATRONE G, HARTMAN R H, CLAWSON A J.Studies of a manganese-iron antagonism in the nutrition of rabbits and baby pigs[J].The Journal of Nutrition, 1959, 67(2):309-317.

[43] NAGALAKSHMI D, SASTRY V R B, AGRAWAL D K, et al.Haematological and immunological response in lambs fed on raw and variously processed cottonseed meal[J].Asian-Australian Journal of Animal Science, 2001, 14(1):21-29.

[44] 林海晶, 夏新成, 王俊峰, 等.诱变选育棉籽粕高效脱毒菌株[J].浙江大学学报:农业与生命科学版, 2011, 37(3):252-258.

[45] 张丛, 李佳, 袁洪水, 等.高效降解棉酚菌株的筛选鉴定及毒性试验[J].中国农学通报, 2012, 28(12):112-117.

[46] 何涛.棉籽粕的发酵脱毒及其在肉仔鸡中的应用研究[D].硕士学位论文.北京:中国农业科学院, 2008.

[47] 孙中超, 方慧英, 诸葛斌, 等.高效降解棉酚菌株的分离鉴定及诱变选育[J].微生物学通报, 2011, 38(8):1166-1171.

[48] 聂存喜, 张文举, 闫理东, 等.棉籽粕源发酵蛋白质饲料的代谢产物研究[J].动物营养学报, 2012, 24(8):1602-1609.

[49] HRONSR R J, WAN P J, KUK M S.Ethanol vapor deactivation of gossypol in cottonseed meal[J].Journal of American Oil Chemists' Society, 1996, 73(10):1337-1339.  

[50] REID B L, GALAVIZ-MORENO S, MAIORINO P M.Evaluation of isopropanol-extracted cottonseed meal for laying hens[J].Poultry Science, 1987, 66(1):82-89.  

[51] RYAN J R, KRATZER F H, GRAU C R, et al.Glandless cottonseed meal for laying and breeding hens and broiler chicks[J].Poultry Science, 1986, 65(5):949-955.  

[52] ELANGOVAN A V, MANDAL A B, JOHRI T S.Comparative performance of broilers fed diets containing processed meals of Bt, parental non-Bt or commercial cotton seeds[J].Asian-Australian Journal of Animal Sciences, 2003, 16(1):57-62.

[53] MANDAL A B, ELANGOVAN A V, SHRIVASTAV A K, et al.Comparison of broiler chicken performance when fed diets containing meals of Bollgard Ⅱ hybrid cotton containing Cry-X gene (Cry1Ac and Cry2Ab gene), parental line or commercial cotton[J].British Poultry Science, 2004, 45(5):657-663.  

[54] JANERO D R, BURGHARDT B.Protection of rat myocardial phospholipids against peroxidative injury through superoxide-(xanthine oxidase)-dependent, iron-promoted fenton chemistry by the male contraceptive gossypol[J].Biochemical Pharmacology, 1988, 37(17):3335-3342.  

[55] LANE A G, STUART R L.Gossypol intake may affect vitamin status of dairy cattle[J].Feedstuffs, 1990, 62(28):13-14.

[56] WILLARD S T, NEUENDORFF D A, LEWIS A W, et al.Effects of free gossypol in the diets of pregnant and postpartum Brahman cows on calf development and cow performance[J].Journal of Animal Science, 1995, 73(2):496-507.

[57] BENDER H S, DEROLF S Z, MISRA H P.Effects of gossypol on the antioxidant defense system of the rat testis[J].Systems Biology in Reproductive Medicine, 1988, 21(2):59-70.  
Outlines

/