ZHU Weiyun, YU Kaifan, MU Chunlong, YANG Yuxiang . Gut Microbiota and Host Nutrition Metabolism in Pigs[J]. Chinese Journal of Animal Nutrition, 2014 , 26(10) : 3046 -3051 . DOI: 10.3969/j.issn.1006-267x.2014.10.016

[1] ADIBI S A.The oligopeptide transporter (Pept-1) in human intestine:biology and function[J].Gastroenterology,1997,113(1):332-340.  

[2] STOLL B,HENRY J,REEDS P J,et al.Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets[J].The Journal of Nutrition,1998,128(3):606-614.

[3] CHEN L X,LI P,WANG J J,et al.Catabolism of nutritionally essential amino acids in developing porcine enterocytes[J].Amino Acids,2009,37(1):143-152.  

[4] CHEN L X,YIN Y L,JOBGEN W S,et al.In vitro oxidation of essential amino acids by jejunal mucosal cells of growing pigs[J].Livestock Science,2007,109(1/2/3):19-23.

[5] RIEDIJK M A,STOLL B,CHACKO S,et al.Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract[J].Proceedings of the National Academy of Sciences of the United States of America,2007,104(9):3408-3413.  

[6] DAI Z L,ZHANG J,WU G Y,et al.Utilization of amino acids by bacteria from the pig small intestine[J].Amino Acids,2010,39(5):1201-1215.  

[7] DAI Z L,LI X L,XI P B,et al.Metabolism of select amino acids in bacteria from the pig small intestine[J].Amino Acids,2012,42(5):1597-1608.  

[8] YANG Y X,DAI Z L,ZHU W Y.Important impacts of intestinal bacteria on utilization of dietary amino acids in pigs[J].Amino Acids,2014,doi:10.1007/s00726-014-1807-y.

[9] WALKER A W,INCE J,DUNCAN S H,et al.Dominant and diet-responsive groups of bacteria within the human colonic microbiota[J].The ISME Journal,2011,5(2):220-230.  

[10] EL KAOUTARI A,ARMOUGOM F,GORDON J I,et al.The abundance and variety of carbohydrate-active enzymes in the human gut microbiota[J].Nature Reviews Microbiology,2013,11(7):497-504.  

[11] DUNCAN S H,HOLTROP G,LOBLEY G E,et al.Contribution of acetate to butyrate formation by human faecal bacteria[J].The British Journal of Nutrition,2004,91(6):915-923.  

[12] TREMAROLI V,BÄCKHED F.Functional interactions between the gut microbiota and host metabolism[J].Nature,2012,489(7415):242-249.  

[13] JHA R,LETERME P.Feed ingredients differing in fermentable fibre and indigestible protein content affect fermentation metabolites and faecal nitrogen excretion in growing pigs[J].Animal,2011,6(4):603.

[14] WONG J M,DE SOUZA R,KENDALL C W C,et al.Colonic health:fermentation and short chain fatty acids[J].Journal of Clinical Gastroenterology,2006,40(3):235-243.  

[15] DAI Z L,WU G Y,ZHU W Y.Amino acid metabolism in intestinal bacteria:links between gut ecology and host health[J].Frontiers in Bioscience,2011,16:1768-1786.

[16] WAUSON E M,ZAGANJOR E,LEE A Y,et al.The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy[J].Molecular Cell,2012,47(6):851-862.  

[17] BANNAI M,TORII K.Digestive physiology of the pig symposium:detection of dietary glutamate via gut-brain axis[J].Journal of Animal Science,2013,91(5):1974-1981.  

[18] DURAFFOURD C,DE VADDER F,GONCALVES D,et al.Mu-opioid receptors and dietary protein stimulate a gut-brain neural circuitry limiting food intake[J].Cell,2012,150(2):377-388.  

[19] BATTERHAM R L,HEFFRON H,KAPOOR S,et al.Critical role for peptide YY in protein-mediated satiation and body-weight regulation[J].Cell Metabolism,2006,4(3):223-233.  

[20] MATSUMOTO M,KIBE R,OOGA T,et al.Impact of intestinal microbiota on intestinal luminal metabolome[J].Scientific Reports,2012,2:233.

[21] WANG W,SHI C Y,ZHANG J S,et al.Molecular cloning,distribution and ontogenetic expression of the oligopeptide transporter PepT1 mRNA in Tibetan suckling piglets[J].Amino Acids,2009,37(4):593-601.  

[22] AITO-INOUE M,LACKEYRAM D,FAN M Z,et al.Transport of a tripeptide,Gly-Pro-Hyp,across the porcine intestinal brush-border membrane[J].Journal of Peptide Science,2007,13(7):468-474.  

[23] ICHIMURA A,HIRASAWA A,HARA T,et al.Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis[J].Prostaglandins & Other Lipid Mediat,2009,89(3/4):82-88.

[24] KIM M H,KANG S G,PARK J H,et al.Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice[J].Gastroenterology,2013,145(2):396-406.  

[25] NICHOLSON J K,HOLMES E,KINROSS J,et al.Host-gut microbiota metabolic interactions[J].Science,2012,336(6086):1262-1267.  

[26] KIMURA I,OZAWA K,INOUE D,et al.The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43[J].Nature Communications,2013,4:1829.

[27] PIEPER R,KRÖGER S,RICHTER J F,et al.Fermentable fiber ameliorates fermentable protein-induced changes in microbial ecology,but not the mucosal response,in the colon of piglets[J].The Journal of Nutrition,2012,142(4):661-667.  

[28] HAENEN D,ZHANG J,DA SILVA C S,et al. A diet high in resistant starch modulates microbiota composition,SCFA concentrations,and gene expression in pig intestine[J].The Journal of Nutrition,2013,143(3): 274-283.  

[29] HAENEN D,ZHANG J,DA SILVA C S,et al.A diet high in resistant starch modulates microbiota composition,SCFA concentrations,and gene expression in pig intestine[J].The Journal of Nutrition,2013,143(3):274-283.  

[30] PUIMAN P,STOLL B,MOLBAK L,et al.Modulation of the gut microbiota with antibiotic treatment suppresses whole body urea production in neonatal pigs[J].American Journal of Physiology:Gastrointestinal and Liver Physiology,2013,304(3):G300-G310.