Roles of Bacteria in First-Pass Intestinal Metabolism of Amino Acids

YANG Yuxiang; MU Chunlong; ZHU Weiyun

doi:10.3969/j.issn.1006-267x.2015.01.003

Chinese Journal of Animal Nutrition >

2015 , Vol. 27 >Issue 1: 15 - 20

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.01.003

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Roles of Bacteria in First-Pass Intestinal Metabolism of Amino Acids

YANG Yuxiang ,
MU Chunlong ,
ZHU Weiyun

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College of Animal Science and Technology, Nanjing Agricultural Uniersity, Nanjing 210095, China

Received date: 2014-07-29

Online published: 2015-01-10

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Abstract

Intestinal bacteria play important roles in nutrient metabolism, which furtherly affect body metabolism. Small intestine is the main region for amnio acids metabolism, and is critical to the host protein nutrition and gut health. However, large amount of amino acids entered into small intestine was degraded during the first-pass intestinal metabolism by bacteria. Amino acid metabolism in the small intestine is compartmentalized, not only segmented, but also layered. Amino acid metabolites, such as polyamine and dipeptide, are important for host gut health. Moreover, urea degradation and subsequent amino acid synthesis by the bacteria might be nutritionally valuable for the host. This article mainly reviewed the roles and out-ways in the first-pass intestinal metabolism of amino acids, metabolic compartments of amino acids, and the impacts of the metabolites on host health of small intestinal bacteria.

Key words： amino acids; first-pass metabolism; small intestine; bacteria

Cite this article

YANG Yuxiang , MU Chunlong , ZHU Weiyun . Roles of Bacteria in First-Pass Intestinal Metabolism of Amino Acids[J]. Chinese Journal of Animal Nutrition, 2015 , 27(1) : 15 -20 . DOI: 10.3969/j.issn.1006-267x.2015.01.003

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