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Histamine as an Abnormal Metabolite in the Rumen of Dairy Cows: Inflammatory Response and Control

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  • Chongqing Key Laboratory of Forage and Herbivores, College of Animal Science and Technology, Southwest University, Chongqing 400716, China

Received date: 2014-08-22

  Online published: 2015-02-09

Abstract

Feeding the high-concentrate and low-roughage diet to dairy cows can increase the concentrations of lactic acid and volatile fatty acids and decrease the ruminal pH, resulting in rumen microflora changes, the release of abnormal metabolic products, such as bacterial endotoxin and histamine, and even cause subacute ruminal acidosis. Histamine is an important inflammatory mediator. After high concentration of histamine is transported to the blood, it plays an important role in inflammation, causing histamine related diseases, so that the dairy cows' production performance is decreased. This paper described the histamine formation and transportation in dairy cows and also discussed the possible mechanisms of the histamine-induced inflammatory responses, finally some methods for reducing histamine release in the rumen and its transportation into the body were proposed.

Cite this article

ZHANG Deguang, DONG Guozhong, NING Lanting, LI Guo . Histamine as an Abnormal Metabolite in the Rumen of Dairy Cows: Inflammatory Response and Control[J]. Chinese Journal of Animal Nutrition, 2015 , 27(2) : 369 -374 . DOI: 10.3969/j.issn.1006-267x.2015.02.006

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