Review

Epigenetic Modulations of Nutrients on Inflammation in Animals and Its Mechanism

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  • College of Animal Science and Technology, Northwest A & F University, Yangling 712100, China

Received date: 2014-09-30

  Online published: 2015-02-09

Abstract

Inflammation is a physiological response of animal body to detrimental stimuli induced by pathogens, damaged tissue and stimulus. The inflammatory response is orchestrated by inflammatory cytokines, which can be regulated through inflammatory mediators and related signaling pathways. Epigenetics is the study of heritable changes which are not caused by changes in the DNA sequence, including DNA methylation, histone modification and non-coding RNAs, etc. Nutrients can regulate inflammatory response, through altering epigenetic modification of the key inflammatory cytokines. This paper reviewed the mechanism of epigenetic modulations of nutrients on inflammation in animals, which were DNA methylation and histone modification.

Cite this article

SHEN Jing, LIU Yanli, GAO Kang, YAO Junhu, YANG Xiaojun . Epigenetic Modulations of Nutrients on Inflammation in Animals and Its Mechanism[J]. Chinese Journal of Animal Nutrition, 2015 , 27(2) : 383 -390 . DOI: 10.3969/j.issn.1006-267x.2015.02.008

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