Effects of Goose Heme on Growth Development, Iron Metabolism and Organic Tissues Element Distribution of Iron Deficiency Anemia Young Rats

XIE Chao, WANG Baowei, GE Wenhua, ZHANG Ming, XU Xiaobo, YUE Bin

doi:10.3969/j.issn.1006-267x.2015.02.011

2015 , Vol. 27 >Issue 2: 408 - 417

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.02.011

Poultry Nutrition

Effects of Goose Heme on Growth Development, Iron Metabolism and Organic Tissues Element Distribution of Iron Deficiency Anemia Young Rats

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Nutrition and Feed Laboratory of China Agriculture Research System Qingdao, Institute of High Quality Waterfowl, Qingdao Agricultural University, Qingdao 266109, China

Received date: 2014-09-22

Online published: 2015-02-09

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Abstract

The experiment was conducted to study the effects of different dosages of goose heme on growth development, iron metabolism and organic tissues element (iron, copper, manganese, zinc and selenium) distribution of iron deficiency anemia (IDA) rats aged from 3 to 7 weeks, and to find the appropriate supplemental level of goose heme and its feeding effect. The same late pregnancy period maternal were selected and fed by low-iron diet, from 15 days after pregnancy to the end of lactation, to establish the IDA model. After that, a total of 180 three-week-old young rats were randomly assigned into 5 groups with 6 replicates per group and 6 rats per replicate. Adding distilled water 10 mL/kg BW (iron deficiency group), 1% FeSO₄ 10 mL/kg BW (FeSO₄ group) and goose heme 0.11 (low-dose group), 0.22 (mid-dose group), 0.33 g/kg BW (high-dose group), fed low iron feed. Normal group had been fed a basal control diet during modling and intervention period. The experiment lasted for 4 weeks. The results showed as follows: 1) the average body gain, final weight and organ indexes (except heart index) in high-dose group had no significant different with normal group (P>0.05). Compared with the iron deficiency group, the hemoglobin, red blood cell, hematokrit, mean corpuscular volume, serum iron and transferrin saturation in blood of young rats in high-dose group were significantly increased (P<0.05 or P<0.01), the erythrocyte hemoglobin distribution width and total iron binding capacity in high-dose group were significantly decreased (P<0.05 or P<0.01), the contents of iron, copper and zinc in heart of rats in high-dose group were significantly increased (P<0.05), the contents of copper and manganese in high-dose group were significantly decreased (P<0.05 or P<0.01). 2)Taking FeSO₄ as iron supplement to intervene IDA model was not significant after long-term use. In conclusion, supplemented with 0.33 g/kg BW goose heme can effective intervene the growth development and hematopoietic ability of IDA young rats, and to make organic tissues element distribution tends to be normal, the effects are better than FeSO₄.

Key words： goose heme; young rats; growth development; blood parameters; element distribution

Cite this article

XIE Chao, WANG Baowei, GE Wenhua, ZHANG Ming, XU Xiaobo, YUE Bin . Effects of Goose Heme on Growth Development, Iron Metabolism and Organic Tissues Element Distribution of Iron Deficiency Anemia Young Rats[J]. Chinese Journal of Animal Nutrition, 2015 , 27(2) : 408 -417 . DOI: 10.3969/j.issn.1006-267x.2015.02.011

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