Review

Regulation of Nitric Oxide Synthesis in Animals by Vitamin A and the Mechanism

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  • College of Animal Science, Inner Mongolia Agricultural University, Huhhot 010018, China

Received date: 2014-10-09

  Online published: 2015-03-18

Abstract

Due to exuberant metabolism or noxious stimulation, animals produce a large amount of nitric oxide (NO), which leads to damage on cellular proteins, lipid membrane and DNA, causes cellular inflammation, and blocks cellular signaling pathways, thereby induces oxidative stresses. Vitamin A can effectively regulate NO production, improve antioxidant level and clean free radicals, and protect cells from cellular inflammation and oxidative stress. This review mainly reviewed the regulation of nitric oxide synthesis by vitamin A and its mechanisms, which might provide some reference for further studies on the regulative mechanisms, scientifically supplementation of vitamin A, and improvement of antioxidant function of body.

Cite this article

SHI Huiyu, YAN Sumei, GUO Xiaoyu . Regulation of Nitric Oxide Synthesis in Animals by Vitamin A and the Mechanism[J]. Chinese Journal of Animal Nutrition, 2015 , 27(3) : 677 -682 . DOI: 10.3969/j.issn.1006-267x.2015.03.003

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