Research Progress of Mechanism of Vitamin D Regulating Development of the Intestine through Wnt Signaling Pathway

SHI Baoshi, XU Ling, ZHANG Xiaolong, LAI Xin, LIU Yajuan, TANG Zhiru

doi:10.3969/j.issn.1006-267x.2015.03.006

Chinese Journal of Animal Nutrition >

2015 , Vol. 27 >Issue 3: 698 - 702

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.03.006

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Research Progress of Mechanism of Vitamin D Regulating Development of the Intestine through Wnt Signaling Pathway

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Key Laboratory for Bio-Feed and Animal Nutrition, College of Animal Science and Technology, Southwest University, Chongqing 400715, China

Received date: 2014-10-21

Online published: 2015-03-18

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Abstract

Wnt signaling pathway is widely present in both vertebrate and invertebrate animal's tissues and organs, it plays a very important role in many organs such as the liver, kidney and intestine. Vitamin D is a group of derivatives of fat-soluble steroid, it doesn't affect the target organ directly, and it works with the vitamin D receptor and exerts its biological effects. Many studies report that vitamin D receptor (VDR) can regulate the development of intestine through the Wnt signaling pathway. This paper reviewed the effect of VDR to Wnt signaling pathway and the Wnt signaling pathway regulating the development of intestine to make some reference for the study on regulating intestine development.

Key words： Wnt signaling pathway; intestine development; vitamin D receptor

Cite this article

SHI Baoshi, XU Ling, ZHANG Xiaolong, LAI Xin, LIU Yajuan, TANG Zhiru . Research Progress of Mechanism of Vitamin D Regulating Development of the Intestine through Wnt Signaling Pathway[J]. Chinese Journal of Animal Nutrition, 2015 , 27(3) : 698 -702 . DOI: 10.3969/j.issn.1006-267x.2015.03.006

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