Effects of Sodium Dehydroacetate on Growth Performance, Serum Biochemical Parameters and Blood Routine Parameters of Weaned Piglets

QU Changbo, LI Bo, ZHANG Lili, WANG Tian

doi:10.3969/j.issn.1006-267x.2015.03.027

2015 , Vol. 27 >Issue 3: 878 - 884

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.03.027

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Effects of Sodium Dehydroacetate on Growth Performance, Serum Biochemical Parameters and Blood Routine Parameters of Weaned Piglets

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College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China

Received date: 2014-10-09

Online published: 2015-03-18

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Abstract

This study was conducted to investigate the effects of sodium dehydroacetate on growth performance, serum biochemical parameters and blood routine parameters of weaned piglets. A total of 288 crossbred (Duroc×Landrace×Yorkshire) piglets were randomly divided into 4 groups, with 6 replicates per group and 12 piglets per replicate, according to the body weight and 1/2 of male and female principles, and the piglets weaned at the age of 23 days. The 4 groups were fed with a basal diet (control group), and the basal diet supplemented with 0.02% (group 1 of test), 0.10% (group 2 of test), 0.20% (group 3 of test) sodium dehydroacetate, respectively. The experiment lasted for 42 days. The results showed that when comparing with the control group: 1) aged from 23 to 52 days, the average daily gain and the average daily feed intake (ADFI) in group 3 of test were significantly decreased by 21.26% and 27.10% (P<0.01), respectively. The ratio of feed to gain (F/G) in group 3 of test was significantly increased by 11.59% (P<0.01). 2) The white blood cell (WBC) number of piglets aged of 52 days in group 3 of test was significantly increased by 43.46% (P<0.05). 3) The serum alanine transaminase (ALT) activity of piglets aged of 52 days in groups 2 and 3 of test was significantly decreased by 55.94% and 63.08% (P<0.01), respectively. The serum urea nitrogen (UN) concentration in groups 1 and 2 of test was significantly increased by 59.83% and 72.48% (P<0.05), and group 3 of test was significantly increased by 110.50% (P<0.01), respectively. The serum creatinine (CRE) concentration in groups 2 and 3 of test was significantly increased by 36.38% and 40.15% (P<0.01), respectively. The results indicate that there are some healthy risks to growth performance and some serum biochemical parameters of weaned piglets by using the high dosage sodium dehydroacetate in the diet.

Key words： sodium dehydroacetate; growth performance; serum biochemical parameters; blood routine parameters

Cite this article

QU Changbo, LI Bo, ZHANG Lili, WANG Tian . Effects of Sodium Dehydroacetate on Growth Performance, Serum Biochemical Parameters and Blood Routine Parameters of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2015 , 27(3) : 878 -884 . DOI: 10.3969/j.issn.1006-267x.2015.03.027

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