[1] KATSNELSON A.Genomics goes beyond DNA sequence[J].Nature, 2010, 465(7295):145.
[2] 王海超, 张乐颖, 刁其玉.营养素对动物表观遗传的影响及其机制[J].动物营养学报, 2014, 26(9):2463-2469.
[3] 王洁, 张心怡, 郝彩丽, 等.组蛋白去乙酰化酶抑制剂的研究进展[J].现代生物医学进展, 2014, 14(14):2783-2785.
[4] 檀琼, 刘全海.组蛋白去乙酰化酶抑制剂的研究进展[J].世界临床药物, 2010, 31(10):616-620.
[5] MYZAK M C, DASHWOOD R H.Histone deacetylases as targets for dietary cancer preventive agents:lessons learned with butyrate, diallyl disulfide, and sulforaphane[J].Current Drug Targets, 2006, 7(4):443-452.
[6] BERGMAN E N.Energy contributions of volatile fatty acids from the gastrointestinal tract in various species[J].Physiological Reviews, 1999, 70(2):567-590.
[7] GASSULL M A, CABRE E.Nutrition in inflammatory bowel diease[J].Current Opinin in Clinical Nutrition and Metabolic Care, 2001, 4(6):561-569.
[8] CHEN J S, FALLER D V, SPANJAARD R A.Short-chain fatty acid inhibitors of histone deacetylases:promising anticancer therapeutics[J].Current Cancer Drug Targets, 2003, 3(3):219-236.
[9] PAJAK B, ORZECHOWSKI A, GAJKOWSKA B.Molecular basis of sodium butyrate-dependent proapoptotic activity in cancer cells[J].Advances in Medical Sciences, 2007, 52:83-88.
[10] LI C J, ELSASSER T H.Butyrate-induced apoptosis and cell cycle arrest in bovine kidney epithelial cells:involvement of caspase and proteasome pathways[J].Journal of Animal Science, 2005, 83(1):89-97.
[11] DAS Z C, GUPTA M K, UHM S J, et al.Increasing histone acetylation of cloned embryos, but not donor cells, by sodium butyrate improves their
in vitro development in pigs[J].Cellular Reprogramming, 2010, 12(1):95-104.
[12] LEU R K L, HU Y, BROWN I L, et al.Effect of high amylose maize starches on colonic fermentation and apoptotic response to DNA-damage in the colon of rats[J].Nutriton&Metabolism, 2009, 6:11.
[13] BLOTTIERE H M, BUECHER B, GALMICHE J P, et al.Molecular analysis of the effect of short-chain fatty acids on intestinal cell proliferation[J].Proceedings of the Nutrition Society, 2003, 62:101-106.
[14] DAVIE J R.Inhibition of histone deacetylase activity by butyrate[J].Journal of Nutrition, 2003, 133(Suppl.7):2485S-2493S.
[15] KIEN C L, PELTIER C P, MANDAL S, et al.Effects of the
in vivo supply of butyrate on histone acetylation of cecum in piglets[J].Journal of Parenteral and Enteral Nutrition, 2008, 32(1):51-56.
[16] KIEN C L, SCHMITZ-BROWN M, SOLLEY T, et al.Increased colonic luminal synthesis of butyric acid is associated with lowered colonic cell proliferation in piglets[J].Journal of Nutrition, 2006, 136:64-69.
[17] MÁTIS G, NEOGRÁDY Z, CSIKÓ G, et al.Effects of orally applied butyrate bolus on histone acetylation and cytochrome P450 enzyme activity in the liver of chicken—a randomized controlled trial[J].Nutriton&Metabolism, 2013, 10:12.
[18] DANNENBERG L O, EDENBERG H J.Epigenetics of gene expression in human hepatoma cells:expression profiling the response to inhibition of DNA methylation and histone deacetylation[J].BMC Genomics, 2006, 7:181.
[19] LEE S J, KRAUTHAUSER C, MADUSKUIE V, et al.Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth
in vitro and
in vivo[J].BMC Cancer, 2011, 11:144.
[20] CHEN Y, SHU W, CHEN W, et al.Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch-1 in Raji cells[J].Basic&Clinical Pharmacology&Toxicology, 2007, 101:427-433.
[21] LIU H L, CHEN Y, CUI G H, et al.Curcumin, a potent antitumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation[J].Acta Pharmacologica Sinica, 2005, 26(5):603-609.
[22] CLARKE J D, DASHWOOD R H, HO E.Multi-targeted prevention of cancer by sulforaphane[J].Cancer Letters, 2008, 269:291-304.
[23] MYZAK M C, DASHWOOD W M, ORNER G A, et al.Sulforaphane inhibits histone deacetylase
in vivo and suppresses tumorigenesis in
Apc-minus mice[J].FASEB Journal, 2006, 20:506-508.
[24] MYZAK M C, TONG P, DASHWOOD W M, et al.Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects[J].Experimental Biology and Medicine, 2007, 232:227-234.
[25] ARIGA T, SEKI T.Antithrombotic and anticancer effects of garlic-derived sulfur compounds:a review[J].Biofactors, 2006, 26:93-103.
[26] LEA M A, RANDOLPH V M, PATEL M.Increased acetylation of histones induced by diallyl disulfide and structurally related molecules[J].International Journal of Oncology, 1999, 15:347-352.
[27] RUIZ P A, BRAUNE A, HOLZLWIMMER G, et al.Quercetin inhibits TNF- induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells[J].The Journal of Nutrition, 2007, 137:1208-1215.
[28] LEE W J, CHEN Y R, TSENG T H.Quercetin induces FasL-related apoptosis, in part, through promotion of histone H3 acetylation in human leukemia HL-60 cells[J].Oncology Reports, 2011, 25:583-591.
[29] PRIYADARSINI R V, VINOTHINI G, MURUGAN R S, et al.The flavonoid quercetin modulates the hallmark capabilities of hamster buccal pouch tumors[J].Nutrition and Cancer-an International Journal, 2011, 63:218-226.
[30] PANDEY M, SHUKLA S, GUPTA S.Promoter demethylation andchromatin remodeling by green tea polyphenols leads to reexpression of GSTP1 in human prostate cancer cells[J].International Journal of Cancer, 2010, 126:2520-2533.
[31] THAKUR V S, GUPTA K, GUPTA S.Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases[J].Carcinogenesis, 2012, 33:377-384.
[32] LI Y, LI X, GUO B.Chemopreventive agent 3, 30-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases[J].Cancer Research, 2010, 70:646-654.
[33] MAJID S, DAR A A, SHAHRYARI V, et al.Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-cell translocation gene 3 in prostate cancer[J].Cancer, 2010, 116:66-76.
[34] WANG L G, BEKLEMISHEVA A, LIU X M, et al.Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer[J].Molecular Carcinogenesis, 2007, 46:24-31.
[35] XIAO L, HUANG Y, ZHEN R, et al.Deficient histone acetylation in acute leukemia and the correction by an isothiocyanate[J].Acta Haematologica, 2010, 123:71-76.
[36] TILI E, MICHAILLE J J, ALDER H, et al.Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGF signaling pathway in SW480 cells[J].Biochemical Pharmacology, 2010, 80:2057-2065.
[37] NIAN H, DELAGE B, HO E, et al.Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides:studies with sulforaphane and garlic organosulfur compounds[J].Environmental and Molecular Mutagenesis, 2009, 50(3):213-221.
[38] DASHWOOD R H, HO E.Dietary histone deacetylase inhibitors:from cells to mice to man[J].Seminars in Cancer Biology, 2007, 17(5):363-369.
[39] MANOLESCU B, ATANASIU V, CERCASOV C, et al.So many options but one choice:the human body prefers alpha-tocopherol.A matter of stereochemistry[J].Journal of Medicine and Life, 2008, 1(4):376-382.
[40] PRASAD K N, KUMAR B, YAN X D, et al.Alpha-tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment:a review[J].Journal of the American College of Nutrition, 2003, 22(2):108-117.
[41] GALLI F, AZZI A.Present trends in vitamin E research[J].Biofactors, 2010, 36(1):33-42.
[42] HAN S N, PANG E, ZINGG J M, et al.Differential effects of natural and synthetic vitamin E on gene transcription in murine T lymphocytes[J].Archives of Biochemistry and Biophysics, 2010, 495(1):49-55.
[43] LI C J, LI R W, ELSASSER T H.Alpha-tocopherol modulates transcriptional activities that affect essential biological processes in bovine cells[J].Gene Regulation and Systems Biology, 2010, 4:109-124.
