Poultry Nutrition

Effects of Intestinal Flora on Intestinal Development, Mucosal Morphology and Immune Organs Development of Chicks

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  • Jiangxi Province Key Laboratory of Animal Nutrition, Jiangxi Agricultural University, Nanchang 330045, China

Received date: 2014-10-29

  Online published: 2015-04-21

Abstract

The gnotobiotic chicken was selected as a model in this study to investigate the effects of colonization with chicken-derived Lactobacillus and chicken cecal microbial on intestinal development, mucosal morphology and immune organs development of chicks. After 21 days aseptic hatching for 80 specific pathogen free (SPF) eggs, a total of 60 healthy chicks were transferred to 3 gnotobiotic isolators (3 groups and 20 chicks for per group), and were fed a basal sterile diet (CT group), the basal sterile diet+Lactobacillus culture (LB group), the basal sterile diet+chicken cecal contents (CC group). Six chicks were slaughtered from 3 groups at 7, 14 and 21 days of age, the intestinal long mucosal morphology and immune organs weight were measured. The results showed as follows: compared with CT group, the jejunum length of chicks added with Lactobacillus or cecal contents was higher, cecal length and volume were lower. The spleen index was significantly higher than that of the CT group (P=0.010). Compared with gnotobiotic chicks, the crypt depth of duodenum, jejunum and ileum was decreased; the villi height/crypt depth (V/C) of duodenum, jejunum and ileum was increased for the chicks added with Lactobacillus or cecal contents. It is concluded that intestinal flora can promote intestinal development, narrow the cecum volume, while promote the development of spleen, enhance immunity.

Cite this article

WU Juanjuan, LAI Shuiming, PAN Ke, TU Xiaoli, ZHU Nianhua . Effects of Intestinal Flora on Intestinal Development, Mucosal Morphology and Immune Organs Development of Chicks[J]. Chinese Journal of Animal Nutrition, 2015 , 27(4) : 1101 -1109 . DOI: 10.3969/j.issn.1006-267x.2015.04.013

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