Effects of Coated ZnO on Growth Performance, Serum Biochemical Indices and Nutrient Apparent Digestibility of Weaner Piglets

ZHU Yujing, SU Xin, LI Fangfang, ZHANG Xin, KUANG Yinggu, ZHENG Lili, GAO Yuan, MEN Lin, GUO Fulai, ZHANG Yong

doi:10.3969/j.issn.1006-267x.2015.06.014

2015 , Vol. 27 >Issue 6: 1779 - 1786

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.06.014

Feed Science and Technology

Effects of Coated ZnO on Growth Performance, Serum Biochemical Indices and Nutrient Apparent Digestibility of Weaner Piglets

Expand

1. College of Animal Sciences and Veterinary Sciences, Shenyang Agricultural University, Shenyang 110866, China;
2. Fujian Shenna Bio. Co., Ltd., Fuzhou 350700, China;
3. Liaoning Debao Agricultural and Animal Husbandry Group Co., Ltd., Shenyang 110171, China

Received date: 2015-01-08

Online published: 2015-06-17

Fold

Abstract

This trial was conducted to study the effects of coated ZnO (C-ZnO) on the growth performance, the serum biochemical indices and nutrient apparent digestibility of weaner piglets, by compared with uncoated ZnO, aimed at research the effects of C-ZnO instead of traditional ZnO, and discussed production practice to reduce the possibility of the dosage of ZnO and enhance its effect. A total of 120 Large-White weaner piglets were randomly divided into 5 groups with 4 replicates per group and 6 piglets per replicate. Piglets in control group were fed a basal diet, the four groups were fed the basal diet supplemented with 2 400 mg/kg ZnO and 1 800, 2 400, 2 740 mg/kg C-ZnO, respectively. The trial lasted for 28 days. The results showed as follows: compared with control group, the average daily gain in the group supplemented with 2 400 mg/kg C-ZnO was increased significantly (P<0.01), the ratio of feed to gain was decreased significantly (P<0.05), and the diarrhea rate was decreased significantly (P<0.01). The average daily gain of 2 400 mg/kg C-ZnO group was significantly higher than that of ZnO group (P<0.01). Compared with control group, serum contents of growth hormone (GH), immunoglobulin G (IgG), immunoglobulin M (IgM) and the digestibility of crude protein and ether extract were significantly increased in 2 400 mg/kg C-ZnO group (P<0.01). Compared with control group, a significant reduction in E. coli number (P<0.01) and a significantly increase in Bifidobacteria number were also observed in 2 400 mg/kg C-ZnO group (P<0.01). Compared with ZnO group, serum GH content was significantly increased (P<0.05) and alkline phosphatase (AKP) activity was significantly decreased (P<0.05) in 2 400 mg/kg C-ZnO group. There were no differences in the growth performance, serum indices and nutrients apparent digestibility between the 1 800 mg/kg C-ZnO and ZnO groups (P>0.05). The diarrhea rate in ZnO groups was significantly decreased (P<0.05) compared with control group, but the other growth performance had no significant difference (P>0.05). In conclusion, supplementation of 2 400 mg/kg coated ZnO in weaner piglets diet can improve the growth performance, improve the nutrient digestible situation and control the diarrhea rate. The effect of 2 400 mg/kg uncoated ZnO is similar to that of 1 800 mg/kg coated one.

Key words： coated ZnO; weaner piglet; growth performance; serum biochemical indices; diarrhea rate; nutrient apparent digestibility

Cite this article

ZHU Yujing, SU Xin, LI Fangfang, ZHANG Xin, KUANG Yinggu, ZHENG Lili, GAO Yuan, MEN Lin, GUO Fulai, ZHANG Yong . Effects of Coated ZnO on Growth Performance, Serum Biochemical Indices and Nutrient Apparent Digestibility of Weaner Piglets[J]. Chinese Journal of Animal Nutrition, 2015 , 27(6) : 1779 -1786 . DOI: 10.3969/j.issn.1006-267x.2015.06.014

References

[1] HILL G M,MAHAN D C,CARTER S D,et al.Effect of pharmacological concentrations of zinc oxide with or without the inclusion of an antibacterial agent on nursery pig performance[J].Journal of Animal Science,2001,79(4):939-941.

[2] POULSEN H D.Zinc and copper as feed additives,growth factors or unwanted environmental factors[J].Journal of Animal Science,1998,7:135-142.

[3] SINGH D P.Synthesis and growth of ZnO nanowires[J].Science of Advanced Materials,2010,2(3):245-272.

[4] WILLIAM H,LATIMER G W.Official methods of analysis of AOAC international[M].Arlington:Association of Official Agriculture Chemists(US),2005:248.

[5] SEELEY H W,VANDEMARK P J,LEE J J.Microbes in action:a laboratory manual of microbiology[M].Freeman:W.H. Freeman,1962:449.

[6] CASTILLO M,MARTIN-ORÙE S M,TAYLOR-PICKARD J A,et al.Use of mannanoligosaccharides and zinc chelate as growth promoters and diarrhea preventative in weaning pigs:effects on microbiota and gut function[J].Journal of Animal Science,2008,86(1):94-101.

[7] VALLE B L,FALCHUK K H.The biochemical basis of zinc physiology[J].Physiological Reviews,1993,73(1):9-118.

[8] DAVIS M E,BROW D C,MAXWELL C V,et al.Effect of phosphorylated mannans and pharmacological additions of zinc oxide on growth and immunocompetence of weanling pigs[J].Journal of Animal Science,2004,82(2):581-587.

[9] DUKES H H.The physiology of domestic animals[M].Literary Licensing,LLC,1955:1020.

[10] KANJANAPRUTHPONG J.Supplementation of milk replacers containing soy protein with threonine,methionine,and lysine in the diets of calves[J].Journal of Dairy Science,1998,81(11):2912-2915.

[11] YU Z P,LE GW,SHI Y H.Effect of zinc sulphate and zinc methionine on growth,plasma growth hormone concentration,growth hormone receptor and insulin like growth factor-Ⅰ gene expression in mice[J].Clinical and Experimental Pharmacology and Physiology,2005,32(4):273-278.

[12] STANLEY C C,WILLIAMS C C,JENNY B F,et al.Effects of feeding milk replacer once versus twice daily on glucose metabolism in hostein and Jersey calves[J].Journal of Dairy Science,2002,85(9):2335-2344.

[13] MALMIOF K.Amino acid in farm animal nutrition metabolism,partition and consequences of imbalance[J].Journal of Agriculture Research,1988,18(4):191-193.

[14] HU C,SONG J,YOU Z,et al.Zinc oxide-montmorillonite hybrid influences diarrhea,intestinal mucosal integrity,and digestive enzyme activity in weaned pigs[J].Biological Trace Element Research,2012,149(2):190-196.

[15] 申俊华,周安国,王之盛,等.包被氧化锌对断奶仔猪腹泻指数及肠道发育的影响[J].畜牧兽医学报,2013,44(6):894-900.

[16] 蔡景义.纳米氧化锌对断奶仔猪生产性能及血液生理生化指标的影响[D].硕士学位论文.雅安:四川农业大学,2004:12-13.

[17] KASAHARA M,ANRAKU Y.Inhibition of the respiratory chain of Escherichia coli by zinc ions[J].Journal of Biochemistry,1972,71(3):777-781.

[18] KATOULI M,MELIN L,JENSEN-WAERN M,et al.The effect of zinc oxide supplementation on the stability of the intestinal flora with special reference to composition of coliforms in weaned pigs[J].Journal of Applied Microbiology,1999,87(4):564-573.

[19] HOGBERG A,LINDBERG J E.Influence of cereal non-starch polysaccharides and enzyme supplementation on digestion site and gut environment in weaned piglets[J].Animal Feed Science and Technology,2004,116(1/2):113-128.

Options

Outlines

模态框（Modal）标题

Abstract

Cite this article

References