Effects of Enterococcus faecalis Substitute for Antibiotic on 
Growth Performance, Diarrhea Rate, Blood Biochemical Parameters and Immune Organs of Weaner Piglets

SHI Zitao, YAO Yanchu, JIANG Shan, XIAO Rong, LIU Zuohua, YANG Feiyun, DONG Guozhong, GUO Zhijun

doi:10.3969/j.issn.1006-267x.2015.06.020

2015 , Vol. 27 >Issue 6: 1832 - 1840

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.06.020

Feed Security

Effects of Enterococcus faecalis Substitute for Antibiotic on
Growth Performance, Diarrhea Rate, Blood Biochemical Parameters and Immune Organs of Weaner Piglets

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1. Chongqing Academy of Animal Sciences, Key Laboratory of Pig Industry Sciences of Agriculture Ministry, Chongqing Key Laboratory of Pig Industry Sciences, Rongchang 402460, China;
2. College of Animal Science and Technology, Southwest University, Beibei 400715, China;
3. Beijing Da Bei Nong Technology Group Co., Ltd., Beijing 100081, China

Received date: 2015-01-04

Online published: 2015-06-17

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Abstract

This trial was conducted to evaluate the effects of Enterococcus faecalis on growth performance, diarrhea rate, blood biochemical parameters and immune organs of weaner piglets. One hundred and twenty crossbred piglets (Duroc × Landrace × Yorkshire) weaned at (28±2) days of age [the average body weight was (7.60±0.81) kg] were selected and divided into 5 groups with 6 replicates per group (3 males and 3 females) and 4 piglets per replicate. The control group was fed a basal diet, antibiotic group was fed the basal diet+100 mg/kg colistin sulphate and 400 mg/kg bacitracin zinc, and the three Enterococcus faecalis groups were fed the basal diet+40, 200 and 1 000 mg/kg Enterococcus faecalis, respectively. The trial lasted for 31 days. The results showed as follows: 1) from 1 to 14 days, the diets supplemented with antibiotic and Enterococcus faecalis had no significant differences in average daily gain (ADG), average daily feed intake (ADFI) and feed/gain (F/G) (P>0.05). From 15 to 31 days, compared with the control and antibiotic groups, 200 and 1 000 mg/kg groups could significantly increased ADFI and ADG of weaner piglets (P<0.01). From 1 to 31 days, compared with the control group, ADFI of weaner piglets in 200 and 1 000 mg/kg groups were significantly increased(P<0.01), and ADG was significantly increased (P<0.05 and P<0.01, respectively). From 1 to 31 days, compared with the antibiotic group, 1 000 mg/kg group could significantly increased ADFI (P<0.01), while 200 and 1 000 mg/kg groups could significantly increased ADG (P<0.05 and P<0.01, respectively). 2) From 1 to 14 days, 40 mg/kg group could significantly decreased diarrhea index and diarrhea rate compared with the control groups (P<0.05). From 15 to 31 days and 1 to 31 days, 40 and 1 000 mg/kg groups could decreased diarrhea rate in some degree compared with the control and antibiotic groups (P>0.05). 3) Compared with the control group, the total protein content in blood in 40, 200 and 1 000 mg/kg groups was significantly increased (P<0.05, P<0.01 and P<0.01, respectively), and the globulin content in 200 and 1 000 mg/kg groups was significantly increased (P<0.05 and P<0.01, respectively). Compared with the antibiotic group, the total protein content of blood in 200 and 1 000 mg/kg groups was significantly increased (P<0.05). Compared with the control group, the albumin/globulin in antibiotic group and 1 000 mg/kg group was significantly decreased (P<0.05), besides, the activities of alanine transferase (ALT) and aspartate transferase (AST) of blood in antibiotic group were significantly decreased (P<0.05), and the activity of alanine transferase (ALT) in 200 mg/kg group was significantly decreased (P<0.05). 4) The liver weight and spleen index in 1 000 mg/kg group had increasing trends compared with the control group (P>0.05), the liver weight in 200 and 1 000 mg/kg groups was significantly increased compared with the antibiotic group (P<0.05). The results suggest that supplementation of Enterococcus faecalis can improve growth performance (feed of 15 to 31 d), decrease diarrhea rate, increase immunity of weaner piglets, and the optimum supplemental level of Enterococcus faecalis is 1 000 mg/kg.

Key words： Enterococcus faecalis; weaner piglets; antibiotic; growth performance; diarrhea rate; blood biochemical parameters; immune organs

Cite this article

SHI Zitao, YAO Yanchu, JIANG Shan, XIAO Rong, LIU Zuohua, YANG Feiyun, DONG Guozhong, GUO Zhijun . Effects of Enterococcus faecalis Substitute for Antibiotic on
Growth Performance, Diarrhea Rate, Blood Biochemical Parameters and Immune Organs of Weaner Piglets[J]. Chinese Journal of Animal Nutrition, 2015 , 27(6) : 1832 -1840 . DOI: 10.3969/j.issn.1006-267x.2015.06.020

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