[1] HU S Y,MAMEDOVA A,HEGDE R S.DNA-binding and regulation mechanisms of the
SIX family of retinal determination proteins[J].Biochemistry,2008,47(11):3586-3594.

[2] LACLEF C,HAMARD G,DEMIGNON J,et al.Altered myogenesis in
Six1-deficient mice[J].Development,2003,130(10):2239-2252.

[3] GRIFONE R,LACLEF C,SPITZ F,et al.Six1 and
Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype[J].Molecular and Cellular Biology,2004,24(14):6253-6267.

[4] CHEYETTE B N R,GREEN P J,MARTIN K,et al.The Drosophila
sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system[J].Neuron,1994,12(5):977-996.

[5] WU W J,HUANG R H,WU Q H,et al.The role of Six1 in the genesis of muscle cell and skeletal muscle development[J].International Journal of Biological Sciences,2014,10(9):983-989.

[6] STIERWALD M,YANZE N,BAMERT R P,et al.The
Sine oculis/Six class family of homeobox genes in jellyfish with and without eyes:development and eye regeneration[J].Developmental Biology,2004,274(1):70-81.

[7] GORDON B S,ELGADO DÍAZ D C,WHITE J P,et al.
Six1 and Six1 cofactor expression is altered during early skeletal muscle overload in mice[J].The Journal of Physiological Sciences,2012,62(5):393-401.

[8] NONOMURA K,TAKAHASHI M,WAKAMATSU Y,et al.Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development[J].Journal of Anatomy,2010,216(1):80-91.

[9] SATO S,IKEDA K,SHIOI G,et al.Regulation of Six1 expression by evolutionarily conserved enhancers in tetrapods[J].Developmental Biology,2012,368(1):95-108.

[10] XU P X,ZHENG W M,HUANG L,et al.Six1 is required for the early organogenesis of mammalian kidney[J].Development,2003,130(14):3085-3094.
[11] KAWAKAMI K,OHTO H,TAKIZAWA T,et al.Identification and expression of six family genes in mouse retina[J].FEBS Letters,1996,393(2/3):259-263.
[12] WEASNER B,SALZER C,KUMAR J P.
Sine oculis,a member of the
SIX family of transcription factors,directs eye formation[J].Developmental Biology,2007,303(2):756-771.

[13] CHRISTENSEN K L,BRENNAN J D G,ALDRIDGE C S,et al.Cell cycle regulation of the human Six1 homeoprotein is mediated by APCCdh1[J].Oncogene,2006,26(23):3406-3414.
[14] BOUCHER C A,CAREY N,EDWARDS Y H,et al.Cloning of the human
SIX1 gene and its assignment to chromosome 14[J].Genomics,1996,33(1):140-142.

[15] WANG H H,JINT H B,LIU H H,et al.Molecular cloning and expression pattern of duck Six1 and its preliminary functional analysis in myoblasts transfected with eukaryotic expression vector[J].Indian Journal of Biochemistry & Biophysics,2014,51(4):271-281.
[16] WU W J,REN Z Q,WANG Y,et al.Molecular characterization,expression patterns and polymorphism analysis of porcine
Six1 gene[J].Molecular Biology Reports,2011,38(4):2619-2632.

[17] XU M,CHEN X L,HUANG Z Q,et al.Prokaryotic expression,purification,and polyclonal antibody preparation,and tissue distribution of porcine
Six1[J].Turkish Journal of Biology,2015,doi:10.3906/biy-1408-1466.
[18] BUCKINGHAM M,RIGBY P W J.Gene regulatory networks and transcriptional mechanisms that control myogenesis[J].Developmental Cell,2014,28(3):225-238.

[19] O'BRIEN J H,HERNANDEZ-LAGUNAS L,ARTINGER K B,et al.MicroRNA-30a regulates zebrafish myogenesis through targeting the transcription factor
Six1[J].Journal of Cell Science,2014,127(10):2291-2301.

[20] BONNIN M A,LACLEF C,BLAISE R,et al.
Six1 is not involved in limb tendon development,but is expressed in limb connective tissue under Shh regulation[J].Mechanisms of Development,2005,122(4):573-585.

[21] DELFINI M-C,DUPREZ D.Ectopic Myf5 or MyoD prevents the neuronal differentiation program in addition to inducing skeletal muscle differentiation,in the chick neural tube[J].Development,2004,131(4):713-723.

[22] FOUGEROUSSE F,DURAND M,LOPEZ S,et al.Six and
Eya expression during human somitogenesis and
MyoD gene family activation[J].Journal of Muscle Research & Cell Motility,2002,23(3):255-264.

[23] OLIVER G,MAILHOS A,WEHR R,et al.
Six3,a murine homologue of the sine oculis gene,demarcates the most anterior border of the developing neural plate and is expressed during eye development[J].Development,1995,121(12):4045-4055.
[24] GRIFONE R,DEMIGNON J,GIORDANI J,et al.Eya1 and Eya2 proteins are required for hypaxial somitic myogenesis in the mouse embryo[J].Developmental Biology,2007,302(2):602-616.

[25] TREMBLAY P,DIETRICH S,MERICSKAY M,et al.A crucial role for Pax3 in the development of the hypaxial musculature and the long-range migration of muscle precursors[J].Developmental Biology,1998,203(1):49-61.

[26] GRIFONE R,DEMIGNON J,HOUBRON C,et al.Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo[J].Development,2005,132(9):2235-2249.

[27] OZAKI H,WATANABE Y,TAKAHASHI K,et al.
Six4,a putative
myogenin gene regulator,is not essential for mouse embryonal development[J].Molecular and Cellular Biology,2001,21(10):3343-3350.

[28] KIRBY R,HAMILTON G M,FINNEGAN D J,et al.
Drosophila homolog of the myotonic dystrophy-associated gene,
SIX5,is required for muscle and gonad development[J].Current Biology,2001,11(13):1044-1049.

[29] KLESERT T R,CHO D H,CLARK J I,et al.Mice deficient in Six5 develop cataracts:implications for myotonic dystrophy[J].Nature Genetics,2000,25(1):105-109.

[30] PARKER M H,SEALE P,RUDNICKI M A.Looking back to the embryo:defining transcriptional networks in adult myogenesis[J].Nature Reviews Genetics,2003,4(7):497-507.

[31] GIORDANI J,BAJARD L,DEMIGNON J,et al.Six proteins regulate the activation of
Myf5 expression in embryonic mouse limbs[J].Proceedings of the National Academy of Sciences,2007,104(27):11310-11315.

[32] SAKAKIBARA I,SANTOLINI M,FERRY A,et al.Six homeoproteins and a linc-RNA at the fast MYH locus lock fast myofiber terminal phenotype[J].PLoS Genetics,2014,10(7):e1004538.
[33] WYZYKOWSKI J C,WINATA T I,MITIN N,et al.Identification of novel
MyoD gene targets in proliferating myogenic stem cells[J].Molecular and Cellular Biology,2002,22(17):6199-6208.

[34] LE GRAND F,GRIFONE R,MOURIKIS P,et al.Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration[J].The Journal of Cell Biology,2012,198(5):815-832.

[35] DAUBAS P,BUCKINGHAM M E.Direct molecular regulation of the myogenic determination gene
Myf5 by Pax3,with modulation by Six1/4 factors,is exemplified by the-111
kb-Myf5 enhancer[J].Developmental Biology,2013,376(2):236-244.

[36] WU W J,REN Z Q,CHEN C,et al.Subcellular localization of different regions of porcine Six1 gene and its expression analysis in C
2C
12 myoblasts[J].Molecular Biology Reports,2012,39(12):9995-10002.

[37] LI Z X,DENG D M,HUANG H C,et al.Overexpression of Six1 leads to retardation of myogenic differentiation in C
2C
12 myoblasts[J].Molecular Biology Reports,2013,40(1):217-223.

[38] WU W J,REN Z Q,ZHANG L,et al.Overexpression of Six1 gene suppresses proliferation and enhances expression of fast-type muscle genes in C
2C
12 myoblasts[J].Molecular and Cellular Biochemistry,2013,380(1/2):23-32.
[39] WU W J,REN Z Q,LIU H L,et al.Core promoter analysis of porcine
Six1 gene and its regulation of the promoter activity by CpG methylation[J].Gene,2013,529(2):238-244.

[40] LIU Y B,CHAKROUN I,YANG D B,et al.Six1 Regulates MyoD expression in adult muscle progenitor cells[J].PloS One,2013,8(6):e67762.
[41] ZHANG H,STAVNEZER E.Ski regulates muscle terminal differentiation by transcriptional activation of
Myog in a complex with
Six1 and
Eya3[J].Journal of Biological Chemistry,2009,284(5):2867-2879.

[42] BESSARAB D A,CHONG S W,SRINIVAS B P,et al.
Six1a is required for the onset of fast muscle differentiation in zebrafish[J].Developmental Biology,2008,323(2):216-228.

[43] YAJIMA H,MOTOHASHI N,ONO Y,et al.
Six family genes control the proliferation and differentiation of muscle satellite cells[J].Experimental Cell Research,2010,316(17):2932-2944.

[44] RELAIX F,DEMIGNON J,LACLEF C,et al.
Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis[J].PLoS Genetics,2013,9(4):e1003425.
[45] FU X,WANG H T,HU P.Stem cell activation in skeletal muscle regeneration[J].Cellular and Molecular Life Sciences,2015:1-15.
[46] NORD H,SKALMAN L N,VON HOFSTEN J.Six1 regulates proliferation of Pax7-positive muscle progenitors in zebrafish[J].Journal of Cell Science,2013,126(8):1868-1880.

[47] NORD H,BURGUIERE A C,MUCK J,et al.Differential regulation of myosin heavy chains defines new muscle domains in zebrafish[J].Molecular Biology of the Cell,2014,25(8):1384-1395.

[48] KOSTEK M C,CHEN Y W,CUTHBERTSON D J,et al.Gene expression responses over 24 h to lengthening and shortening contractions in human muscle:major changes in
CSRP3,
MUSTN1,
SIX1,and
FBXO32[J].Physiological Genomics,2007,31(1):42-52.

[49] NIRO C,DEMIGNON J,VINCENT S,et al.
Six1 and
Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotome[J].Developmental Biology,2010,338(2):168-182.

[50] HETZLER K L,COLLINS B C,SHANELY R A,et al.The homoeobox gene Six1 alters myosin heavy chain isoform expression in mouse skeletal muscle[J].Acta Physiologica,2014,210(2):415-428.

[51] QUIAT D,VOELKER K A,PEI J M,et al.Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6[J].Proceedings of the National Academy of Sciences of the United States of America,2011,108(25):10196-10201.

[52] AN C I,GANIO E,HAGIWARA N.Trip12,a HECT domain E3 ubiquitin ligase,targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells[J].Skeletal Muscle,2013,3(1):11.
[53] RICHARD A F,DEMIGNON J,SAKAKIBARA I,et al.Genesis of muscle fiber-type diversity during mouse embryogenesis relies on
Six1 and
Six4 gene expression[J].Developmental Biology,2011,359(2):303-320.