Effect of Dietary Chitosan on Growth Performance, Lipid Metabolism, Non-Specific Immune Function and Intestinal Health of Juvenile Jian Carp (Cyprinus carpio var. Jian)

HUANG Xinwei; YANG Shasha; LIU Yi; FAN Tao; MING Wei; LIN Rongnan; WEN Anxiang

doi:10.3969/j.issn.1006-267x.2015.07.016

2015 , Vol. 27 >Issue 7: 2106 - 2114

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.07.016

Molecular Nutrition

Effect of Dietary Chitosan on Growth Performance, Lipid Metabolism, Non-Specific Immune Function and Intestinal Health of Juvenile Jian Carp (Cyprinus carpio var. Jian)

HUANG Xinwei ,
YANG Shasha ,
LIU Yi ,
FAN Tao ,
MING Wei ,
LIN Rongnan ,
WEN Anxiang

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College of Life Sciences, Sichuan Agricultural University, Ya'an 625014, China

Received date: 2015-02-03

Online published: 2015-07-07

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Abstract

This experiment was conducted to investigate the effects of chitosan oligosaccharides on growth performance, lipid metabolism and non-specific immune function and intestinal health of juvenile Jian carp (Cyprinus carpio var. Jian). A total of 225 juvenile Jian carp with an average body weight of (8.78±0.38) g were randomly divided in 5 groups with 3 replicates per group and 15 fish per replicate. The fish in the 5 groups were fed the diets supplemented with 0 (control group), 0.3%, 0.6%, 0.9% and 1.5% of chitosan oligosaccharides for 80 days, respectively. The results showed as follows: compared with the control group, specific growth rate and weight gain rate in different chitosan oligosaccharides groups were increased (P>0.05); plasma triglyceride and total cholesterol contents of 0.6% group were significantly lower than those of other groups(P<0.05), while plasma high density lipoprotein cholesterol content was significantly higher than that of other groups (P<0.05); plasma malondialdehyde content of each chitosan oligosaccharides group was significantly lower than that of control group (P<0.05), and plasma total antioxidant capacity of 0.6% group was significantly higher than that of control group (P<0.05); the phagocytic rate of leukocyte and intestinal fold density of each chitosan oligosaccharides group were significantly higher than those of control group (P<0.05), and intestinal wall thickness of 0.6% and 0.9% groups was significantly bigger than that of control group (P<0.05); the amount of Escherichia coli in intestine of chitosan oligosaccharides group was significantly lower than that of control group (P<0.05), while the amounts of Bifidobacterium and Lactobacillus in intestine of 0.6% and 0.9% groups were significantly higher than those of control group (P<0.05). Collectively, these findings suggest that the chitosan oligosaccharides can improve growth performance and non-specific immune function, and adjust lipid metabolism of juvenile Jian carp. According to the X extreme value analysis of regression curves of non-specific immunity and intestinal health, it can be concluded that the optimal supplemental level of chitosan oligosaccharides in the diet of juvenile Jian carp is 0.86% to 1.09%.

Key words： chitosan oligosaccharides; juvenile Jian carp (Cyprinus carpio var.Jian); growth performance; lipid metabolism; immune; intestine

Cite this article

HUANG Xinwei , YANG Shasha , LIU Yi , FAN Tao , MING Wei , LIN Rongnan , WEN Anxiang . Effect of Dietary Chitosan on Growth Performance, Lipid Metabolism, Non-Specific Immune Function and Intestinal Health of Juvenile Jian Carp (Cyprinus carpio var. Jian)[J]. Chinese Journal of Animal Nutrition, 2015 , 27(7) : 2106 -2114 . DOI: 10.3969/j.issn.1006-267x.2015.07.016

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