Effects of Dietary Anti-Microbial Peptides and Coated Zinc Oxide on Growth Performance and Serum Biochemical Indices of Weaning Piglets

LI Fangfang; SU Hang; ZHANG Yong; KUANG Yinggu; GAO Yuan; MENG Ling; GUO Fulai; ZHU Yujing

doi:10.3969/j.issn.1006-267x.2015.09.019

2015 , Vol. 27 >Issue 9: 2811 - 2819

DOI: https://doi.org/10.3969/j.issn.1006-267x.2015.09.019

Feed Science and Technology

Effects of Dietary Anti-Microbial Peptides and Coated Zinc Oxide on Growth Performance and Serum Biochemical Indices of Weaning Piglets

LI Fangfang ,
SU Hang ,
ZHANG Yong ,
KUANG Yinggu ,
GAO Yuan ,
MENG Ling ,
GUO Fulai ,
ZHU Yujing

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1. College of Animal Sciences and Veterinary Sciences, Shenyang Agricultural University, Shenyang 110866, China;
2. Fujian Shenna Bio Engineering Co., Ltd., Fujian 350700, China;
3. Liaoning Debao Argi-animal Husbandry Co., Ltd., Shenyang 110171, China

Received date: 2015-03-23

Online published: 2015-09-12

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Abstract

This experiment was conducted to investigate the effects of dietary anti-microbial peptides (C-AMPs) and coated zinc oxide (C-ZnO) on growth performances, serum biochemical indices, nutrient apparent digestibility and feacal microflora of weaning piglets. A total of 160 large white piglets with body weight of (6.98±0.05) kg were randomly allotted to 4 groups with 4 replicates per group and 10 piglets per replicate. The four groups were fed the basal diet, the basal diet+0.5 mg/kg C-AMPs (C-AMPs group), the basal diet+1 800 mg/kg C-ZnO (C-ZnO group) and the basal diet+0.5 mg/kg C-AMPs+1 800 mg/kg C-ZnO (C-AMPs+C-ZnO group). The trial lasted for 28 days. The results showed as follows:1) compared with the control group, dietary supplemented with C-AMPs and C-ZnO or two together, the average daily gain and average daily feed intake significantly increased (P<0.05 or P<0.01), the diarrhea rate of weaning piglets significantly reduced (P<0.01). 2) Compared with the control group, dietary supplemented with C-AMPs and C-ZnO significantly increased serum growth hormone content (P<0.05), significantly decreased serum alkaline phosphatase activity (P<0.05); dietary supplemented with both C-AMPs and C-ZnO significantly increased the content of immunoglobulin G, growth hormone, interleukin 2 and interleukin 6 in serum (P<0.01), dietary supplemented with C-AMPs significantly increased serum CSF-Ab content (P<0.01). 3) Compared with the control group, dietary supplemented with C-ZnO significantly increased the apparent digestibility of crude protein, ether extract and organism matter (P<0.05). 4) Compared with the control group, dietary supplemented with C-AMPs and C-ZnO or two together significantly reduced the number of E.coli in excrement (P<0.01), but the number of Bifidobacterium significant increased (P<0.01). The results indicate that supplementation of C-AMPs and C-ZnO in the diet can improve the growth performance and nutrient apparent digestibility, also can regulate the immune related and the balance of intestinal flora.

Key words： compound antimicrobial peptides; coated ZnO; weaning piglets; growth performance; serum biochemical indices; digestbility; microflora

Cite this article

LI Fangfang , SU Hang , ZHANG Yong , KUANG Yinggu , GAO Yuan , MENG Ling , GUO Fulai , ZHU Yujing . Effects of Dietary Anti-Microbial Peptides and Coated Zinc Oxide on Growth Performance and Serum Biochemical Indices of Weaning Piglets[J]. Chinese Journal of Animal Nutrition, 2015 , 27(9) : 2811 -2819 . DOI: 10.3969/j.issn.1006-267x.2015.09.019

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