Review

Regulation of Adenosine 5'-Monophosphate-Activated Protein Kinase in Mammalian Ovary Development and Mechanisms

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  • Animal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China

Received date: 2015-04-28

  Online published: 2015-10-15

Abstract

Adenosine 5'-monophosphate-activated protein kinase (AMPK) regulation pathway is the central part of the cellular energy metabolism, which plays a vital role in the female reproductive tract development.Numerous studies have explored the relationship between AMPK and ovary development, and the role of AMPK mediates glucose, insulin-like growth factor-1 (IGF-1), follicle stimulating hormone (FSH) and adiponectin.In this paper, the advances in the regulation of AMPK in the mammalian ovary development were reviewed in order to promoting further the research on application of AMPK for cure of ovary disease.

Key words: AMPK; ovary; glucose; IGF-1; FSH; adiponectin

Cite this article

XU Mengmeng, CHE Long, ZHANG Pan, WU De, XU Shengyu . Regulation of Adenosine 5'-Monophosphate-Activated Protein Kinase in Mammalian Ovary Development and Mechanisms[J]. Chinese Journal of Animal Nutrition, 2015 , 27(10) : 3006 -3011 . DOI: 10.3969/j.issn.1006-267x.2015.10.003

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