Molecular Nutrition

High Concentrate Diets Induces Changes of Rumen Fluid Metabolome and Impacts on Health of Dairy Cows

  • MA Jiaoli ,
  • DONG Guozhong ,
  • WU Jianbo
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  • Chongqing Key Laboratory of Forage and Herbivores, College of Animal Science and Technology, Southwest University, Chongqing 400716, China

Received date: 2015-07-08

  Online published: 2016-01-22

Abstract

In today's dairy production, the metabolic diseases caused by high concentrate diet are a common problem. Traditional studies on nutritionally metabolic diseases just focused on one or several biomarkers for investigating the occurrence and development of high concentrate diet-related metabolic diseases, and the results were often not complete and even might be erroneous. Metabolomics, as an important omics technology, can make a comprehensive analysis of the metabolic status of dairy cows under a specific circumstance so as to clarify the changes of the complex life system. This paper mainly reviewed the changes of the lactating dairy cows' rumen fluid metabolome caused by high concentrate diet and the impacts on the health of dairy cows.

Cite this article

MA Jiaoli , DONG Guozhong , WU Jianbo . High Concentrate Diets Induces Changes of Rumen Fluid Metabolome and Impacts on Health of Dairy Cows[J]. Chinese Journal of Animal Nutrition, 2016 , 28(1) : 27 -34 . DOI: 10.3969/j.issn.1006-267x.2016.01.005

References

[1] IQBAL S,ZABELI Q,MAZZOLARI A,et al.Feeding barley grain steeped in lactic acid modulates rumen fermentation patterns and increases milk fat content in dairy cows[J].Journal of Dairy Science,2009,92(12):6023-6032.

[2] ZEBELI Q,DIJKSTRA J,TAFAJ M,et al.Modeling the adequacy of dietary fiber in dairy cows based on the responses of ruminal pH and milk fat production to composition of the diet[J].Journal of Dairy Science,2008,91(5):2046-2066.

[3] NOCEK J E.Bovine acidosis:implications on laminitis[J].Journal of Dairy Science,1997,80(5):1005-1028.

[4] AMETAJ B N,BRADFORD B J,BOBE G,et al.Strong relationships between mediators of the acute phase response and fatty liver in dairy Cows[J].Canadian Journal of Animal Science,2005,85(2):165-175.

[5] EMMANUEL D G V,DUNN S M,AMETAJ B N.Feeding high proportions of barley grain stimulates an inflammatory response in dairy cows[J].Journal of Dairy Science,2008,91(2):606-614.

[6] JENKINS T C,MCGUIRE M A.Major advances in nutrition:impact on milk composition[J].Journal of Dairy Science,2006,89(4):1302-1310.

[7] ZEBELI Q,AMETAJ B N.Relationships between rumen lipopolysaccharide and mediators of inflammatory response with milk fat production and efficiency in dairy cows[J].Journal of Dairy Science,2009,92(8):3800-3809.

[8] AMETAJ B N.A systems veterinary approach in understanding transition cow diseases:metabolomics[C]//Proceedings of the 4th international symposium on dairy cow nutrition and milk quality.Beijing:Institute of Animal Sciences of Chinese Academy of Agricultural Sciences,2015:78-85.

[9] 郭福存,赵兴绪.营养基因组学研究最新进展[J].饲料研究,2007(2):14-18.

[10] 孙会增,刘建新.营养代谢组学及其在奶牛营养研究中的应用[J].中国畜牧杂志,2014,50(11):81-85.

[11] MVLLER M,KERSTEN S.Nutrigenomics:goals and strategies[J].Nature Reviews Genetics,2003,4(4):315-322.

[12] 王小艳.中国荷斯坦奶牛泌乳相关营养代谢组学研究[D].硕士学位论文.哈尔滨:东北农业大学,2013:17-19.

[13] DRACKLEY J K,DANN H M.New concepts in nutritional management of dry cows[J].Advances in Dairy Technology,2005,17:11-23.

[14] INGVARTSEN K L.Feeding-and management-related diseases in the transition cow:physiological adaptations around calving and strategies to reduce feeding-related diseases[J].Animal Feed Science and Technology,2006,126(3/4):175-213.

[15] TAJIMA K,ARAI S,OGATA K,et al.Rumen bacterial community transition during adaptation to high-grain diet[J].Anaerobe,2000,6(5):273-284.

[16] AMETAJ B N,ZEBELI Q,SALEEM F,et al.Metabolomics reveals unhealthy alterations in rumen metabolism with increased proportion of cereal grain in the diet of dairy cows[J].Metabolomics,2010,6(4):583-594.

[17] SALEEM F,AMETAJ B N,BOUATRA S,et al.A metabolomics approach to uncover the effects of grain diets on rumen health in dairy cows[J].Journal of Dairy Science,2012,95(11):6606-6623.

[18] SALEEM F,BOUATRA S,GUO A C,et al.The bovine ruminal fluid metabolome[J].Metabolomics,2013,9(2):360-378.

[19] TURLIN E,PERROTTE-PIQUEMAL M,DANCHIN A.Regulation of the early steps of 3-phenylpropionate catabolism in Escherichia coli[J].Journal of Molecular Microbiology and Biotechnology,2001,3(1):127-133.

[20] SATTER L D,ESDALE W J.In vitro lactate metabolism by ruminal ingesta[J].Applied and Environmental Microbiology,1968,16(5):680-688.

[21] ÖRLYGSSON J,ANDERSON R,SVENSSON B H.Alanine as an end product during fermentation of monosaccharides by Clostridium strain P2[J].Antonie van Leeuwenhoek,1995,68(4):273-280.

[22] GOULD G W.Symposium on bacterial spores:paper Ⅳ.Germination and the problem of dormancy[J].Journal of Applied Bacteriology,1970,33(1):34-49.

[23] HOOGENRAAD N J,HIRD F J R.The chemical composition of rumen bacteria and cell walls from rumen bacteria[J].British Journal of Nutrition,1970,24(1):119-127.

[24] MCALIAN A B,SMITH R H.Degradation of nucleic acids in the rumen[J].British Journal of Nutrition,1973,29(2):331-345.

[25] TRENT M S,STEAD C M,TRAN A X,et al.Diversity of endotoxin and its impact on pathogenesis[J].Journal of Endotoxin Research,2006,12(4):205-223.

[26] AMETAJ B U,ZEBELI Q,IQBAL S.Nutrition,microbiota,and endotoxin-related diseases in dairy cows[J].Revista Brasileira de Zootecnia,2010,39:433-444.

[27] GOLOMBESKI G L,KALSCHEUR K F,HIPPEN A R,et al.Slow-release urea and highly fermentable sugars in diets fed to lactating dairy cows[J].Journal of Dairy Science,2006,89(11):4395-4403.

[28] HIGHSTREET A,ROBINSON P H,ROBISON J,et al.Response of Holstein cows to replacing urea with a slowly rumen released urea in a diet high in soluble crude protein[J].Livestock Science,2010,129(1/2/3):179-185.

[29] BLOODD C,HENDERSON J A.Veterinary medicine[M].2nd ed.Baltimore:Williams & Wilkins,1963:107.

[30] DAVIS E J,DE ROPP R S.Metabolic origin of urinary methylamine in the rat[J].Nature,1961,190(4776):636-637.

[31] HILL K J,MANGAN J L.The formation and distribution of methylamine in the ruminant digestive tract[J].Biochemical Journal,1964,93(1):39-45.

[32] NEILL A R,GRIME D W,DAWSON R M C.Conversion of choline methyl groups through trimethylamine into methane in the rumen[J].Biochemical Journal,1978,170(3),529-535.

[33] YU P H,LU L X, FAN H,et al.Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in lipopolysaccharide-induced pulmonary inflammation[J].The American Journal of Pathology,2006,168(3):718-726.

[34] GOODLAD R A.Some effects of diet on the mitotic index and the cell cycle of the ruminal epithelium of sheep[J].Quarterly Journal of Experimental Physiology,1981,66(4):487-499.

[35] NAGARAJA T G,BARTLEY E E,FINA L R,et al.Relationship of rumen gram-negative bacteria and free endotoxin to lactic acidosis in cattle[J].Journal of Animal Science,1978,47(6):1329-1337.

[36] BERTIN Y,GIRARDEAU J P,CHAUCHEYRAS-DURAND F,et al.Enterohaemorrhagic Escherichia coli gains a competitive advantage by using ethanolamine as a nitrogen source in the bovine intestinal content[J].Environmental Microbiology,2011,13(2):365-377.

[37] THIENNIMITR P,WINTER S E,WINTER M G,et al.Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota[J].Proceedings of the National Academy of Sciences of the United States of America,2011,108(42):17480-17485.

[38] KHAFIPOUR E,LI S C,PLAIZIER J C,et al.Rumen microbiome composition determined using two nutritional models of subacute ruminal acidosis[J].Applied and Environmental Microbiology,2009,75(22):7115-7124.

[39] PUROHIT V,BODE J C,BODE C,et al.Alcohol,intestinal bacterial growth,intestinal permeability to endotoxin,and medical consequences:summary of a symposium[J].Alcohol,2008,42(5):349-361.

[40] BAILEY S R,MARR C M,ELLIOTT J.Identification and quantification of amines in the equine caecum[J].Research in Veterinary Science,2003,74(2):113-118.

[41] MUROOKA Y,DOI N,HARADA T.Distribution of membrane-bound monoamine oxidase in bacteria[J].Applied and Environmental Microbiology,1979,38(4):565-569.

[42] YAMASHITA Y,BOWEN W H,BURNE R A,et al.Role of the Streptococcus mutans GTF genes in caries induction in the specific-pathogen-free rat model[J].Infection and Immunity,1993,61(9):3811-3817.

[43] WILLARD F L,KODRAS R.Survey of chemical compounds tested in vitro against rumen protozoa for possible control of bloat[J].Applied and Environmental Microbiology,1967,15(5):1014-1019.

[44] LIJINSKY W.N-nitroso compounds in the diet[J].Mutation Research,1999,443(1/2):129-138.

[45] SOULIOTIS V L,HENNEMAN J R,REED C D,et al.DNA adducts and liver DNA replication in rats during chronic exposure to N-nitrosodimethylamine (NDMA) and their relationships to the dose-dependence of NDMA hepatocarcinogenesis[J].Mutation Research,2002,500(1/2):75-87.
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