[1] OH-I S,SHIMIZU H,SATOH T,et al.Identification of Nesfatin-1 as a satiety molecule in the hypothalamus[J].Nature,2006,443(7112):709-712.
[2] SHIMIZU H,OH-I S,HASHIMOTO K,et al.Peripheral administration of nesfatin-1 reduces food intake in mice:the leptin-independent mechanism[J].Endocrinology,2009,150(2):662-671.
[3] LENTS C A,BARB C R,HAUSMAN G J,et al.Effects of nesfatin-1 on food intake and LH secretion in prepubertal gilts and genomic association of the porcine NUCB2 gene with growth traits[J].Domestic Animal Endocrinology,2013,45(2):89-97.
[4] GAIGÉ S,BONNET M S,TARDIVEL C,et al.c-Fos immunoreactivity in the pig brain following deoxynivalenol intoxication:focus on NUCB2/nesfatin-1 expressing neurons[J].NeuroToxicology,2013,34:135-149.
[5] PALASZ A,KRYSTANEK M,WORTHINGTON J,et al.Nesfatin-1,a unique regulatory neuropeptide of the brain[J].Neuropeptides,2012,46(3):105-112.
[6] GONZALEZ R,SHEPPERD E,THIRUPPUGAZH V,et al.Nesfatin-1 regulates the hypothalamo-pituitary-ovarian axis of fish[J].Biology of Reproduction,2012,87(4):84.
[7] KOHNO D,NAKATA M,MAEJIMA Y,et al.Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding[J].Endocrinology,2008,149(3):1295-1301.
[8] 宋敏,田园,方富贵.Nesfatin-1与生殖[J].生理科学进展,2014,45(6):439-441.
[9] ZHANG A Q,LI X L,JIANG C Y,et al.Expression of nesfatin-1/NUCB2 in rodent digestive system[J].World Journal of Gastroenterology,2010,16(14):1735-1741.
[10] STENGEL A,GOEBEL M,YAKUBOV I,et al.Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa[J].Endocrinology,2009,150(1):232-238.
[11] GARCíA-GALIANO D,PINEDA R,ILHAN T,et al.Cellular distribution,regulated expression,and functional role of the anorexigenic peptide,NUCB2/nesfatin-1,in the testis[J].Endocrinology,2012,153(4):1959-1971.
[12] FEIJíO-BANDíN S,RODRíGUEZ-PENAS D,GARCíA-RÙA V,et al.Nesfatin-1 in human and murine cardiomyocytes:synthesis,secretion,and mobilization of GLUT-4[J].Endocrinology,2013,154(12):4757-4767.
[13] PAN W H,HSUCHOU H,KASTIN A J.Nesfatin-1 crosses the blood-brain barrier without saturation[J].Peptides,2007,28(11):2223-2228.
[14] FOO K S,BRISMAR H,BROBERGER C.Distribution and neuropeptide coexistence of nucleobindin-2 mRNA/nesfatin-like immunoreactivity in the rat CNS[J].Neuroscience,2008,156(3):563-579.
[15] 朱宇旌,丁兰,张勇,等.胰岛素对促性腺激素释放激素分泌及活性的调控[J].动物营养学报,2013,25(1):1-7.
[16] VARRICCHIO E,RUSSOLILLO M G,RUSSO F,et al.Expression and immunohistochemical detection of Nesfatin-1 in the gastrointestinal tract of Casertana pig[J].Acta Histochemica,2014,116(4):583-587.
[17] GUO F F,XU L,GAO S L,et al.The effects of nesfatin-1 in the paraventricular nucleus on gastric motility and its potential regulation by the lateral hypothalamic area in rats[J].Journal of Neurochemistry,2015,132(3):266-275.
[18] 王文杰,蒋正尧.nesfatin-1对大鼠迷走复合体内葡萄糖感受神经元和胃扩张敏感神经元兴奋性的作用[J].齐鲁医学杂志,2010,25(3):225-227.
[19] STENGEL A,TACH Y.Nesfatin-1-role as possible new potent regulator of food intake[J].Regulatory Peptides,2010,163(1/2/3):18-23.
[20] GARCíA-GALIANO D,NAVARRO V M,ROA J,et al.The anorexigenic neuropeptide,Nesfatin-1,is indispensable for normal puberty onset in the female rat[J].The Journal of Neuroscience,2010,30(23):7783-7792.
[21] MOHAN H,UNNIAPPAN S.Ontogenic pattern of nucleobindin-2/nesfatin-1 expression in the gastroenteropancreatic tissues and serum of Sprague Dawley rats[J].Regulatory Peptides,2012,175(1/2/3):61-69.
[22] 王尧尧,李冉,李运生,等.Nesfatin-1对初情期雌性大鼠促性腺激素及其mRNA表达的影响[J].中国农业大学学报,2015,20(3):139-145.
[23] 张志红.下丘脑输注Nesfatin-1对肝脏AMPK/TORC2/AKT信号通路的影响[D].博士学位论文.重庆:重庆医科大学,2012.
[24] 吴丹冬,杨刚毅,李钶,等.NUCB2 siRNA对肝细胞胰岛素信号通路及细胞凋亡的影响[J].免疫学杂志,2014(10):860-864.
[25] YANG M L,ZHANG Z H,WANG C,et al.Nesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistance[J].Diabetes,2012,61(8):1959-1968.
[26] WEISMAN R,COHEN A,GASSER S M.TORC2-a new player in genome stability[J].EMBO Molecular Medicine,2014,6(8):995-1002.
[27] NAKATA M,MANAKA K,YAMAMOTO S,et al.Nesfatin-1 enhances glucose-induced insulin secretion by promoting Ca2+ influx through L-type channels in mouse islet β-cells[J].Endocrine Journal,2011,58(4):305-313.
[28] YOSTEN G L C,SAMSON W K.Nesfatin-1 exerts cardiovascular actions in brain:possible interaction with the central melanocortin system[J].American Journal of Physiology Regulatory, Integrative and Comparative Physiology,2009,297(2):R330-R336.
[29] MIMEE A,SMITH P M,FERGUSON A V.Nesfatin-1 influences the excitability of neurons in the nucleus of the solitary tract and regulates cardiovascular function[J].American Journal of Physiology Regulatory, Integrative and Comparative Physiology,2012,302(11):R1297-R1304.
[30] KÓNCZÓL K,PINTÉR O,FERENCZI S,et al.Nesfatin-1 exerts long-term effect on food intake and body temperature[J].International Journal of Obesity,2012,36(12):1514-1521.
[31] FOO K S,BRAUNER H,ÓSTENSON C G.Nucleobindin-2/nesfatin in the endocrine pancreas:distribution and relationship to glycaemic state[J].Journal of Endocrinology,2010,204(3):255-263.
[32] GONZALEZ R,REINGOLD B K,GAO X D,et al.Nesfatin-1 exerts a direct,glucose-dependent insulinotropic action on mouse islet β- and MIN6 cells[J].Journal of Endocrinology,2011,208(3):R9-R16.
[33] MOHAN H,RAMESH N,MORTAZAVI S,et al.Nutrients differentially regulate nucleobindin-2/nesfatin-1 in vitro in cultured stomach ghrelinoma (MGN3-1) cells and in vivo in male mice[J].PLoS One,2014,9(12):e11502.
[34] GONZALEZ R,PERRY R L S,GAO X,et al.Nutrient responsive nesfatin-1 regulates energy balance and induces glucose-stimulated insulin secretion in rats[J].Endocrinology,2011,152(10):3628-3637.
[35] 秦小云,王伯钧,伍善广,等.NUCB2/Nesfatin-1在DIO大鼠下丘脑中的表达[J].中国临床解剖学杂志,2014,32(6):704-707.
[36] 吴博,刘重斌,董缪武,等.重复性饥饿/再投喂对大鼠下丘脑NUCB 2表达影响[J].中国公共卫生,2010,39(3):313-314.
[37] 李清春,管洪在,陈曦,等.禁食前后小鼠胃黏膜NUCB 2的变化[J].青岛大学医学院学报,2010,46(3):206-208.
[38] HATEF A,SHAJAN S,UNNIAPPAN S.Nutrient status modulates the expression of Nesfatin-1 encoding nucleobindin 2A and 2B mRNAs in zebrafish gut,liver and brain[J].General and Comparative Endocrinology,2014,215:51-60.
[39] SENIN L L,AL-MASSADI O,BARJA-FERNANDEZ S,et al.Regulation of NUCB2/Nesfatin-1 production in rat's stomach and adipose tissue is dependent on age,testosterone levels and lactating status[J].Molecular and Cellular Endocrinology,2015,411:105-112.
[40] BONNET M S,OUELAA W,TILLEMENT V,et al.Gastric distension activates NUCB2/nesfatin-1-expressing neurons in the nucleus of the solitary tract[J].Regulatory Peptides,2013,187:17-23.
