REVIEW

Dietary Tryptophan Affects Immunomodulatory in Livestock and Poultry

  • BAI Miaomiao ,
  • LIU Hongnan ,
  • WU Xin ,
  • LIU Gang ,
  • TOSSOU Myrlene Carine ,
  • XU Kang ,
  • XI Qianyun ,
  • YIN Yulong
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  • 1. College of Animal Science, South China Agricultural University, Guangzhou 510642, China;
    2. Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Engineering Research Center of Healthy Livestock, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China

Received date: 2015-08-24

  Online published: 2016-02-19

Abstract

As an essential amino acid, tryptophan has a function of regulation of immune response in animals. Metabolites of tryptophan including indoleamine 2,3-dioxygenase (IDO), kynurenine, quinolinic acid and melatonin, may improve immunity of the organism, induce anti-inflammatory response and prevent cancer. These metabolites play a role in inhibition of T lymphocyte proliferation, elevation of immunoglobulin levels in the blood and promotion of antigen-presenting organizations in tissues. This review summarized the effects and mechanism of tryptophan and its metabolites on immune functions in livestock and poultry.

Cite this article

BAI Miaomiao , LIU Hongnan , WU Xin , LIU Gang , TOSSOU Myrlene Carine , XU Kang , XI Qianyun , YIN Yulong . Dietary Tryptophan Affects Immunomodulatory in Livestock and Poultry[J]. Chinese Journal of Animal Nutrition, 2016 , 28(2) : 361 -368 . DOI: 10.3969/j.issn.1006-267x.2016.02.008

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