REVIEW

Adenosine Monophosphate-Activated Protein Kinase Signal Transduction Pathways:Regulation Mechanism in Process of Cow Ketosis Occurrence and Development

  • DONG Jihong ,
  • WU Jinjie ,
  • WANG Xichun ,
  • FENG Shibin ,
  • DING Hongyan ,
  • LIU Guowen ,
  • LI Xinwei ,
  • LI Xiaobing ,
  • WANG Zhe ,
  • LI Yu
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  • 1. College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China;
    2. College of Veterinary Medicine, Jilin University, Changchun 130062, China

Received date: 2015-10-15

  Online published: 2016-04-11

Abstract

Cow ketosis is a common nutritional and metabolic disease during perinatal, which has caused tremendous losses to the dairy industry. Related energy metabolic hormones have undergone tremendous changes when ketosis occurs, mainly including glucagon and insulin. Adenosine monophosphate-activated protein kinase(AMPK) is considered to be an energy sensor, some energy metabolic hormones can cause changes of AMPK activity. This article focused on the role of glucagon and insulin in AMPK signal transduction pathways aimed at providing theoretical support for further research in cow ketosis.

Cite this article

DONG Jihong , WU Jinjie , WANG Xichun , FENG Shibin , DING Hongyan , LIU Guowen , LI Xinwei , LI Xiaobing , WANG Zhe , LI Yu . Adenosine Monophosphate-Activated Protein Kinase Signal Transduction Pathways:Regulation Mechanism in Process of Cow Ketosis Occurrence and Development[J]. Chinese Journal of Animal Nutrition, 2016 , 28(4) : 1035 -1041 . DOI: 10.3969/j.issn.1006-267x.2016.04.010

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