REVIEW

Reproductive Toxicities and Functional Mechanisms of Female Animals Induced by Deoxynivalenol and Zearalenone

  • GAO Shuang ,
  • LIANG Zhen ,
  • DENG Junliang ,
  • YANG Yanyi ,
  • CHEN Yun
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  • Key Laboratory of Animal Disease & Human Health of Sichuan Province, Key Laboratory of Environmental Hazard and Animal Disease of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China

Received date: 2015-11-02

  Online published: 2016-04-11

Abstract

Fusarium mycotoxins, which included zearalenone and deoxynivalenol, are widespread in cereals and feedstuffs. Previous studies showed that ZEA and DON could result in reproductive disorders of female domestic animals in vivo and in vitro, such as the functional and morphological alterations in both reproductive organs and germ-cell, and the disorder of sex hormones secretion. This paper summarizes individual and combined reproductive toxicities of DON and ZEA in female domestic animals. Also, the related mechanisms of the two mycotoxins were discussed.

Cite this article

GAO Shuang , LIANG Zhen , DENG Junliang , YANG Yanyi , CHEN Yun . Reproductive Toxicities and Functional Mechanisms of Female Animals Induced by Deoxynivalenol and Zearalenone[J]. Chinese Journal of Animal Nutrition, 2016 , 28(4) : 1042 -1049 . DOI: 10.3969/j.issn.1006-267x.2016.04.011

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