Effects of Low Dose Zearalenone and Adsorbent on Growth Performance, Serum Biochemical and Antioxidant Indices of Growing-Laying Hens

WU Yuchao; YANG Weiren; YANG Zaibin; JIANG Shuzhen; ZHANG Guiguo; JIANG Xinchao

doi:10.3969/j.issn.1006-267x.2016.04.023

2016 , Vol. 28 >Issue 4: 1137 - 1144

DOI: https://doi.org/10.3969/j.issn.1006-267x.2016.04.023

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Effects of Low Dose Zearalenone and Adsorbent on Growth Performance, Serum Biochemical and Antioxidant Indices of Growing-Laying Hens

WU Yuchao ,
YANG Weiren ,
YANG Zaibin ,
JIANG Shuzhen ,
ZHANG Guiguo ,
JIANG Xinchao

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College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China

Received date: 2015-11-06

Online published: 2016-04-11

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Abstract

This experiment was conducted to study the effects of low dose of zearalenone on growth performance, serum biochemical and antioxidant indices of growing-laying hens, and the detoxification effect of adsorbent Calibrin-A(CA) was also evaluated. Seven hundred and twenty 70-day-old Hy-Line Brown laying hens were randomly divided into 4 groups with 5 replicates and 36 hens in each replicate. The control group was given the basal diet. The test group 1 was fed the basal diet with 0.15% CA. The test group 2 was fed the control diet in which corn gluten meal was replaced by naturally contaminated corn gluten meal(zearalenone=0.4 mg/kg). The test group 3 was fed the test group 2 diet with 0.15% CA. The experiment comprised 7 days of adaptation and 49 days of measurement period. The results showed as follows:1) low dose of zearalenone and 0.15% CA had no significant effects on the growth performance of growing-laying hens(P>0.05). 2) Low dose of zearalenone significantly increased low density lipoprotein, cholesterol and uric acid concentrations on day 25 in the serum(P<0.05), and the addition of CA significantly decreased the low density lipoprotein, cholesterol and uric acid concentrations in the serum(P<0.05). 3) Low dose of zearalenone significantly decreased the activities of glutathione peroxidase(on day 25 and 47) and total superoxide dismutase(on day 47)(P<0.05), but the malondialdehyde content in the serum was significantly increased(on day 25 and 47)(P<0.05). Compared with low dose of zearalenone group, the addition of CA significantly increased the activities of glutathione peroxidase(on day 47) and total superoxide dismutase(on day 47)(P<0.05), and significantly decreased the malondialdehyde content in the serum(on day 25 and 47)(P<0.05). This experiment shows that 0.4 mg/kg zearalenone does not affect the growth performance of growing-laying hens, but it has significant effects on serum biochemical and antioxidant indices, and addition of CA can partly attenuate the detrimental effects of the zearalenone feeding.

Key words： growing-laying hens; zearalenone; adsorbent; growing performance; metabolism; antioxidant

Cite this article

WU Yuchao , YANG Weiren , YANG Zaibin , JIANG Shuzhen , ZHANG Guiguo , JIANG Xinchao . Effects of Low Dose Zearalenone and Adsorbent on Growth Performance, Serum Biochemical and Antioxidant Indices of Growing-Laying Hens[J]. Chinese Journal of Animal Nutrition, 2016 , 28(4) : 1137 -1144 . DOI: 10.3969/j.issn.1006-267x.2016.04.023

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