REVIEW

Enteroendocrine and Nutrient Sensing System

  • GAO Kan ,
  • MU Chunlong ,
  • YU Kaifan ,
  • ZHU Weiyun
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  • Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, Laboratory of Gastrointestinal Microbiology, Nanjing Agricultural University, Nanjing 210095, China

Received date: 2015-12-29

  Online published: 2016-06-27

Abstract

A variety of nutrients and chemicals in the gastrointestinal (GI) tract exert physiologic effects via enteroendocrine and nutrient sensing system. As a part of enteroendocrine and nutrient sensing system, enteroendocrine cells can detect luminal nutrients via nutrient sensing receptors (amino acids sensing receptors, fatty acids sensing receptors, glucose sensing receptors, etc.). Enteroendocrine cells not only can regulate nutrient absorption and metabolism, but also can secret kinds of gut-brain peptides (glucagon-like peptide-1, peptide YY and cholecystokinin, etc.). Gut-brain peptides through the gut-brain axis, which is composed of central neuron system, automatic nervous system and enteric nervous system, regulate host feeding behaviors and other physiologic functions. This review summarized recent advances on animal enteroendocrine system, gut-brain axis and nutrient sensing receptors.

Cite this article

GAO Kan , MU Chunlong , YU Kaifan , ZHU Weiyun . Enteroendocrine and Nutrient Sensing System[J]. Chinese Journal of Animal Nutrition, 2016 , 28(6) : 1633 -1640 . DOI: 10.3969/j.issn.1006-267x.2016.06.001

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