Effects of Arginine Infusion through Jugular Vein on Serum Biochemical and Immune Indices of Dairy Cows at Mid-Lactation

DING Luoyang; LIANG Xianghuan; WANG Mengzhi; ZHANG Jun; WANG Hongrong; ZHOU Gang; ZHANG Xin; XU Qiaoyun

doi:10.3969/j.issn.1006-267x.2016.06.033

2016 , Vol. 28 >Issue 6: 1899 - 1906

DOI: https://doi.org/10.3969/j.issn.1006-267x.2016.06.033

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Effects of Arginine Infusion through Jugular Vein on Serum Biochemical and Immune Indices of Dairy Cows at Mid-Lactation

DING Luoyang ,
LIANG Xianghuan ,
WANG Mengzhi ,
ZHANG Jun ,
WANG Hongrong ,
ZHOU Gang ,
ZHANG Xin ,
XU Qiaoyun

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1. College of Animal and Technology, Yangzhou University, Yangzhou 225009, China;
2. Experimental Farm of Yangzhou University, Yangzhou 225009, China

Received date: 2015-12-30

Online published: 2016-06-27

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Abstract

This study was conducted to investigate the effects of arginine infusion through jugular vein on serum biochemical and immune indices of dairy cows at mid-lactation. A 3×3 Latin square trail was used. Six healthy lactating cows at similar lactation stages with similar body weight, parities, days in milk, milk yield and body condition were selected and divided into 3 groups (2 for each group), which were casein group (control group), arginine group (infused 37.66 g/d), and alanine group (equal nitrogen to arginine group, infused 77.24 g/d); three periods of test were carried out, and each period lasted for 22 d (7-day infusion period plus 15-day interval period). Blood was collected before morning feeding at the last day of infusion period to detect serum biochemical and immune indices. The results showed as follows: the concentrations of total protein, immunoglobulin G (IgG), tumor necrosis factor α (TNF-α) in serum in arginine group were significantly higher than those in other groups (P<0.05), the concentrations of interleukin 1 (IL-1) and the ratio of albumin to globulin in arginine group were significantly higher than those in alanine group (P<0.05), and the number of somatic cells in milk in arginine group was significantly lower than that in other 2 groups (P<0.05), but no significant differences were found in the activities of gluamic-pyruvic transaminase and glutamic oxalacetic transaminase, and the concentrations of immunoglobulin A (IgA), immunoglobulin E (IgE) and interleukin 6 (IL-6) among groups (P>0.05). In conclusion, arginine infusion can promote immunity performance of lactating cows and the passive immunity of fetus in some degree by increasing serum total protein, IgG, IL-1 and TNF-α concentrations.

Key words： jugular vein infusion; arginine; immune globulin; cytokine; somatic cells

Cite this article

DING Luoyang , LIANG Xianghuan , WANG Mengzhi , ZHANG Jun , WANG Hongrong , ZHOU Gang , ZHANG Xin , XU Qiaoyun . Effects of Arginine Infusion through Jugular Vein on Serum Biochemical and Immune Indices of Dairy Cows at Mid-Lactation[J]. Chinese Journal of Animal Nutrition, 2016 , 28(6) : 1899 -1906 . DOI: 10.3969/j.issn.1006-267x.2016.06.033

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