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Effects of Composite Specific Immunoglobulin of Yolk on Growth, Diarrhea and Immunity of Calves Aged from 18 to 28 Days

  • YANG Chuntao ,
  • DIAO Qiyu ,
  • SI Bingwen ,
  • MA Junnan ,
  • KONG Luxin ,
  • TU Yan
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  • Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing Key Laboratory for Dairy Cow Nutrition, Key Laboratory of Feed Biotechnology, The Ministry of Agriculture, Beijing 100081, China

Received date: 2016-01-18

  Online published: 2016-07-28

Abstract

This study aimed to investigate the effects of dietary supplementation of composite specific immunoglobulin (Ig) of yolk (IgY) on growth, diarrhea and immunity of calves aged from 18 to 28 days. Twenty new born Chinese Holstein bull calves were selected and fed fresh milk until 10 days of age, then were randomly assigned to one of two groups. Calves were fed a basal diet (CON group) or the basal diet daily supplemented with 45 mg/kg BW composite specific (IGY group). The pre-experiment was from 11 to 17 days of age when a milk replacer was gradually used, after that the formal experiment was carried out from 18 to 28 days of age. Weight of calves was recorded at 18 and 28 days of age, respectively. Feed intake and fecal score were recorded daily. Blood samples were obtained by jugular venipuncture from calves at 28 days of age. Serum total antioxidant capacity (T-AOC), the activity alkaline phosphatase (AKP) and concentrations of serum Ig, nitric oxide (NO) and lysozyme (LZM) were determined. The results showed as follows: dietary supplementation of IgY had no significant effects on average daily gain and feed to gain ratio (P>0.05). Compared with CON group, IGY group significantly decreased fecal score and diarrhea incidence (P<0.05). Serum concentrations of IgG, IgM and IgA in IGY group were significantly higher than those in CON group (P<0.01), and were increased by 7.19%, 5.71% and 8.50%, respectively. Serum T-AOC in IGY group was significantly higher compared to that in CON group (P<0.01), however, serum NO concentration was significantly decreased in CON group (P<0.05). Serum concentration of LZM in IGY group was significantly lower compared to that in CON group (P<0.01), but serum activity of AKP was not influenced (P>0.05). In summary, diets supplemented with composite specific IgY improve immunity and the capacity of resist to external stress by increasing serum Ig concentrations and antioxidant capacity, and developing antigen-antibody reaction of IgY to decrease diarrhea incidence and promote health of calves.

Cite this article

YANG Chuntao , DIAO Qiyu , SI Bingwen , MA Junnan , KONG Luxin , TU Yan . Effects of Composite Specific Immunoglobulin of Yolk on Growth, Diarrhea and Immunity of Calves Aged from 18 to 28 Days[J]. Chinese Journal of Animal Nutrition, 2016 , 28(7) : 2176 -2183 . DOI: 10.3969/j.issn.1006-267x.2016.07.023

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