[1] 曾俊,杨刚毅.脂肪细胞因子与胰岛素抵抗的关系及其机制研究新进展[J].成都医学院学报,2011,6(1):78-82.
[2] QIAO L P,YOO H S,MADON A,et al.Adiponectin enhances mouse fetal fat deposition[J].Diabetes,2012,61(12):3199-3207.
[3] KIM J Y,VAN DE WALL E,LAPLANTE M,et al.Obesity-associated improvements in metabolic profile through expansion of adipose tissue[J].Journal of Clinical Investigation,2007,117(9):2621-2637.
[4] KOTANI Y,YOKOTA I,KITAMURA S,et al.Plasma adiponectin levels in newborns are higher than those in adults and positively correlated with birth weight[J].Clinical Endocrinology,2004,61(4):418-423.
[5] KUBOTA N,YANO W,KUBOTA T,et al.Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake[J].Cell Metabolism,2007,6(1):55-68.
[6] QIAO L P,KINNEY B,SCHAACK J,et al.Adiponectin inhibits lipolysis in mouse adipocytes[J].Diabetes,2011,60(5):1519-1527.
[7] ANTHONSEN M W,RÖNNSTRAND L,WERNSTEDT C,et al.Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties
in vitro[J].Journal of Biological Chemistry,1998,273(1):215-221.
[8] MOHAMMADZADEH G,ZARGHAMI N.Hypoadiponectinemia in obese subjects with type Ⅱ diabetes:a close association with central obesity indices[J].Journal of Research Medical Sciences,2011,16(6):713-723.
[9] SKRABAL C A,CZAJA J,HONZ K,et al.Adiponectin-its potential to predict and prevent coronary artery disease[J].The Thoracic and Cardiovascular Surgeon,2011,59(4):201-206.
[10] KYRIAZI E,TSIOTRA P C,BOUTATI E,et al.Effects of adiponectin in TNF-α,IL-6,IL-10 cytokine production from coronary artery disease macrophages[J].Hormone and Metabolic Research,2011,43(8):537-544.
[11] KERN P A,DI GREGORIO G T,LU T,et al.Adiponectin expression from human adipose tissue:relation to obesity,insulin resistance,and tumor necrosis factor-α expression[J].Diabetes,2003,52(7):1779-1785.
[12] GUO H H,LIU G L,ZHONG R M,et al.Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells[J].Lipids in Health and Disease,2012,11:10.
[13] LI Y,XU S Q,MIHAYLOVA M M,et al.AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice[J].Cell Metabolism,2011,13(4):376-388.
[14] JÄGER S,HANDSCHIN C,ST-PIERRE J,et al.AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α[J].Proceedings of the National Academy of Sciences of the United States of America,2007,104(29):12017-12022.
[15] ROHAS L M,ST-PIERRE J,ULDRY M,et al.A fundamental system of cellular energy homeostasis regulated by PGC-1α[J].Proceedings of the National Academy of Sciences of the United States of America,2007,104(19):7933-7938.
[16] CANTÓ C,GERHART-HINES Z,FEIGE J N,et al.AMPK regulates energy expenditure by modulating NAD
+ metabolism and SIRT1 activity[J].Nature,2009,458(7241):1056-1060.
[17] MILLER R A,CHU Q W,LE LAY J,et al.Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling[J].Journal of Clinical Investigation,2011,121(6):2518-2528.
[18] 陈灰.脂联素激活AMPK信号通路调控奶牛肝细胞脂代谢的相关机制[D].硕士学位论文.长春:吉林大学,2013.
[19] LI L,PAN R P,LI R,et al.Mitochondrial biogenesis and peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation by physical activity:intact adipocytokine signaling is required[J].Diabetes,2011,60(1):157-167.
[20] TRAYHURN P.Hypoxia and adipose tissue function and dysfunction in obesity[J].Physiological Reviews,2013,93(1):1-21.
[21] GE J F,QI C C,ZHOU J N.Imbalance of leptin pathway and hypothalamus synaptic plasticity markers are associated with stress-induced depression in rats[J].Behavioural Brain Research,2013,249:38-43.
[22] LI Y C,ZHENG X L,LIU B T,et al.Regulation of ATGL expression mediated by leptin
in vitro in porcine adipocyte lipolysis[J].Molecular and Cellular Biochemistry,2010,333(1/2):121-128.
[23] KERSHAW E E,SCHUPP M,GUAN H P,et al.PPARγ regulates adipose triglyceride lipase in adipocytes
in vitro and
in vivo[J].American Journal of Physiology Endocrinology and Metabolism,2007,293(6):E1736-E1745.
[24] RICHARD A J,STEPHENS J M.The role of JAK-STAT signaling in adipose tissue function[J].Biochimica et Biophysica Acta:Molecular Basis of Disease,2014,1842(3):431-439.
[25] CERNKOVICH E R,DENG J B,BOND M C,et al.Adipose-specific disruption of signal transducer and activator of transcription 3 increases body weight and adiposity[J].Endocrinology,2008,149(4):1581-1590.
[26] FRVHBECK G.Intracellular signalling pathways activated by leptin[J].Biochemical Journal,2006,393(1):7-20.
[27] KOLTES D A,SPURLOCK D M.Appendix A.Translocation of adipose triglyceride lipase to the lipid droplet increased with leptin treatment in bovine adipocytes[M]//KOLTES D.Novel mechanisms involved with lipid metabolism in adipose tissue of dairy cows.Iowa:Iowa State University,2013:150-175.
[28] MANNING B D,CANTLEY L C.AKT/PKB signaling:navigating downstream[J].Cell,2007,129(7):1261-1274.
[29] ROMAN E A F R,REIS D,ROMANATTO T,et al.Central leptin action improves skeletal muscle AKT,AMPK,and PGC1α activation by hypothalamic PI3K-dependent mechanism[J].Molecular and Cellular Endocrinology,2010,314(1):62-69.
[30] SLOAN C,TUINEI J,NEMETZ K,et al.Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted
ob/ob mice[J].Diebetes,2011,60(5):1424-1434.
[31] BASTARD J P,LAGATHU C,CARON M,et al.Point-counterpoint:interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis[J].Journal of Applied Physiology,2007,102(2):821-822.
[32] RUDERMAN N B,KELLER C,RICHARD A M,et al.Interleukin-6 regulation of AMP-activated protein kinase:potential role in the systemic response to exercise and prevention of the metabolic syndrome[J].Diabetes,2006,55(Suppl.2):S48-S54.
[33] GLUND S,DESHMUKH A,LONG Y C,et al.Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle[J].Diabetes,2007,56(6):1630-1637.
[34] KELLY M,GAUTHIER M S,SAHA A K,et al.Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle:association with changes in cAMP,energy state,and endogenous fuel mobilization[J].Diabetes,2009,58(9):1953-1960.
[35] YANG Y Q,JU D P,ZHANG M T,et al.Interleukin-6 stimulates lipolysis in porcine adipocytes[J].Endocrine,2008,33(3):261-269.
[36] GEHART H,KUMPF S,ITTNER A,et al.Mapk signalling in cellular metabolism:stress or wellness?[J].EMBO Reports,2010,11(11):834-840.
[37] MACDONALD T L,WAN Z X,FRENDO-CUMBO S,et al.IL-6 and epinephrine have divergent fiber type effects on intramuscular lipolysis[J].Journal of Applied Physiology,2013,115(10):1457-1463
[38] MAURY E,NOËL L,DETRY R,et al.
In vitro hyperresponsiveness to tumor necrosis factor-αcontributes to adipokine dysregulation in omental adipocytes of obese subjects[J].The Journal of Clinical Endocrinology & Metabolism,2009,94(4):1393-1400.
[39] 李艳杰.肿瘤坏死因子-α对大鼠前体脂肪细胞增殖与分化的影响[D].硕士学位论文.杨凌:西北农林科技大学,2003.
[40] KENNELL J A,MACDOUGALD O A.Wnt signaling inhibits adipogenesis through β-catenin-dependent and-independent mechanisms[J].Journal of Biological Chemistry,2005,280(25):24004-24010.
[41] KANAZAWA A,TSUKADA S,KAMIYAMA M,et al.Wnt5b partially inhibits canonical Wnt/β-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes[J].Biochemical and Biophysical Research Communications,2005,330(2):505-510.
[42] ROSS S E,HEMATI N,LONGO K A,et al.Inhibition of adipogenesis by Wnt signaling[J].Science,2000,289(5481):950-953.
[43] LIU J J,WANG H,ZUO Y,et al.Functional interaction between peroxisome proliferator-activated receptor γ and β-catenin[J].Molecular and Cellular Biology,2006,26(15):5827-5837.
[44] QADIR A S,LEE H L,BAEK K H,et al.Msx2 is required for TNF-α-induced canonical Wnt signaling in 3T3-L1 preadipocytes[J].Biochemical and Biophysical Research Communications,2011,408(3):399-404.
[45] TAKADA I,KOUZMENKO A P,KATO S.Molecular switching of osteoblastogenesis versus adipogenesis:implications for targeted therapies[J].Expert Opinion on Therapeutic Targets,2009,13(5):593-603.
[46] SUZAWA M,TAKADA I,YANAGISAWA J,et al.Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade[J].Nature Cell Biology,2003,5(3):224-230.
[47] LI H Y,CHEN X,GUAN L Z,et al.MiRNA-181a regulates adipogenesis by targeting tumor necrosis factor-α (TNF-α) in the porcine model[J].PLoS One,2013,8(10):e71568.
[48] RUAN H,POWNALL H J,LODISH H F.Troglitazone antagonizes tumor necrosis factor-α-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-κB[J].Journal of Biological Chemistry,2003,278(30):28181-28192.
[49] ZHANG H H,HALBLEIB M,AHMAD F,et al.Tumor necrosis factor-α stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP[J].Diabetes,2002,51(10):2929-2935.
[50] MARTIN S,PARTON R G.Lipid droplets:a unified view of a dynamic organelle[J].Nature Reviews Molecular Cell Biology,2006,7(5):373-378.
[51] RYDÉN M,ARVIDSSON E,BLOMQVIST L,et al.Targets for TNF-α-induced lipolysis in human adipocytes[J].Biochemical and Biophysical Research Communications,2004,318(1):168-175.
[52] LORENTE-CEBRIÁN S,BUSTOS M,MARTI A,et al.Eicosapentaenoic acid inhibits tumour necrosis factor-α-induced lipolysis in murine cultured adipocytes[J].The Journal of Nutritional Biochemistry,2012,23(3):218-227.
[53] NISHIMURA F,IWAMOTO Y,MINESHIBA J,et al.Periodontal disease and diabetes mellitus:the role of tumor necrosis factor-α in a 2-way relationship[J].Journal of Periodontology,2003,74(1):97-102.
[54] LUMENG C N,BODZIN J L,SALTIEL A R.Obesity induces a phenotypic switch in adipose tissue macrophage polarization[J].Journal of Clinical Investigation,2007,117(1):175-184.
[55] WEISBERG S P,MCCANN D,DESAI M,et al.Obesity is associated with macrophage accumulation in adipose tissue[J].Journal of Clinical Investigation,2003,112(12):1796-1808.
[56] ROTTER V,NAGAEV I,SMITH U,et al.Interleukin-6(IL-6) induces insulin resistance in 3T3-L1 adipocyteas and is,like IL-8 and tumor necrosis factor-α,overexpressed in human fat cells from insulin-resistant subjects[J].Journal of Biological Chemistry,2003,278(46):45777-45784.
[57] ZHOU W J,YANG P,LIU L,et al.Transmembrane tumor necrosis factor-alpha sensitizes adipocytes to insulin[J].Molecular and Cellular Endocrinology,2015,406:78-86.
[58] ZHANG W Z,CHAI B X,LI J Y,et al.Effect of des-acyl ghrelin on adiposity and glucose metabolism[J].Endocrinology,2008,149(9):4710-4716.
[59] GONG H,NI Y,GUO X,et al.Resistin promotes 3T3-L1 preadipocyte differentiation[J].European Journal of Endocrinology,2004,150(6):885-892.
[60] 白翠玲,罗丹,刘艳芬,等.抵抗素成熟肽的制备及其对猪葡萄糖和脂肪代谢的影响[J].动物医学进展,2013,34(11):46-50.
[61] KIM S J,NIAN C L,MCLNTOSH C H S.Resistin knockout mice exhibit impaired adipocyte glucose-dependent insulinotropic polypeptide receptor (GIPR) expression[J].Diabetes,2013,62(2):471-477.
[62] REVERCHON M,RAMÉ C,COGNIÉ J,et al.Resistin in dairy cows:plasma concentrations during early lactation,expression and potential role in adipose tissue[J].PLoS One,2014,9(3):e93198.
[63] RODRIGUEZ-PACHECO F,NOVELLE M G,VAZQUEZ M J,et al.Resistin regulates pituitary lipid metabolism and inflammation
in vivo and
in vitro[J].Mediators of Inflammation,2013,2013:479739.
[64] GERKOWICZ A,PIETRZAK A,SZEPIETOWSKI J C,et al.Biochemical markers of psoriasis as a metabolic disease[J].Folia Histochemica et Cytobiologica,2012,50(2):155-170.
[65] DE BOER T N,VAN SPIL W E,HUISMAN A M,et al.Serum adipokines in osteoarthritis;comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage[J].Osteoarthritis and Cartilage,2012,20(8):846-853.
[66] CHOE J Y,BAE J,JUNG H Y,et al.Serum resistin level is associated with radiographic changes in hand osteoarthritis:cross-sectional study[J].Joint Bone Spine,2012,79(2):160-165.
