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Effects of Nutritional Compound Additive Feeding Patterns on Immune Function and Swine Fever Antibody Titer of Growing Pigs

  • ZHONG Jiayou ,
  • CHEN Daiwen ,
  • YU Bing ,
  • HE Jun ,
  • ZHENG Ping ,
  • MAO Xiangbing ,
  • HUANG Zhiqing ,
  • LUO Junqiu ,
  • LUO Yuheng ,
  • YU Jie
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  • Animal Nutrition Institute, Sichuan Agricultural University;Key Laboratory of Animal Disease-Resistance Nutrition, China Ministry of Education, Chengdu 611130, China

Received date: 2016-04-15

  Online published: 2016-11-18

Abstract

The experiment was conducted to investigate the effects of nutritional compound additive (NCA) feeding patterns on immune function and swine fever (SF) antibody titer of growing pigs. A total of 24 healthy Duroc×Landrace×Yorkshire growing pigs with an initial average body weight of (40.5±2.3) kg were allocated to 4 groups with 6 replicates per group and 1 pig per pen with randomized complete block design according to similar weight and gender. On the 7th day, each pig was given SF vaccine. Pigs feeding in this experiment were divided into two stages:7 d before and 28 d after vaccination. The whole trial lasted for 35 d. Pigs in the control group were fed a basal diet, and in the experimental groups were fed diets supplemented with 0.1% NCA during early, late and whole stage of the trail, respectively. The results showed that feeding NCA during the entire trail significantly increased the serum HC antibody titer of pigs at the 21st day compared with the control group (P<0.05). Compared with the control group and feeding NCA before vaccination, feeding NCA during entire period significantly increased the serum HC antibody titer of pigs at the 28th day (P<0.05). Compared with the control group, feeding NCA after vaccination and during entire experiment significantly decreased the blood CD3+ amount at the 21st day (P<0.05), while the blood CD3+ amount was significantly decreased by feeding NCA during entire period compared with the other groups (P<0.05). Compared with the control group, feeding NCA during entire period significantly increased serum immunoglobulin contents of pigs at the 21st and 35th day (P<0.05), and feeding NCA before vaccination or during entire period significantly increased serum superoxide dismutase activity and total antioxidant capacity (P<0.05), while latter significantly decreased malondialdehyde content of pigs (P<0.05). In conclusion, different feeding patterns of NCA affect the levels of HC antibody titer and immunoglobulin and antioxidant capacity of growing pigs, and feeding NCA for entire period is better than a shorter period.

Cite this article

ZHONG Jiayou , CHEN Daiwen , YU Bing , HE Jun , ZHENG Ping , MAO Xiangbing , HUANG Zhiqing , LUO Junqiu , LUO Yuheng , YU Jie . Effects of Nutritional Compound Additive Feeding Patterns on Immune Function and Swine Fever Antibody Titer of Growing Pigs[J]. Chinese Journal of Animal Nutrition, 2016 , 28(11) : 3611 -3617 . DOI: 10.3969/j.issn.1006-267x.2016.11.030

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