Effects of Vaccarin and Puerain on Lactation Performance, Serum Hormone and Antioxidant Indexes of Lactating Sows

WANG Fangfang; WU Hongzhi; DIAO Huajie; WANG Zhilong; DENG Xiaomin; DIAO Xinping

doi:10.3969/j.issn.1006-267x.2016.12.032

Chinese Journal of Animal Nutrition >

2016 , Vol. 28 >Issue 12: 3977 - 3987

DOI: https://doi.org/10.3969/j.issn.1006-267x.2016.12.032

Molecular Nutrition

Effects of Vaccarin and Puerain on Lactation Performance, Serum Hormone and Antioxidant Indexes of Lactating Sows

WANG Fangfang ,
WU Hongzhi ,
DIAO Huajie ,
WANG Zhilong ,
DENG Xiaomin ,
DIAO Xinping

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College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China

Received date: 2016-06-07

Online published: 2016-12-17

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Abstract

The objective of this study was to investigate the effects of vaccarin and puerain on lactation performance, serum hormone and antioxidant indexes of lactating sows. The trial used a 2×2 factorial random design, the main effects were vaccarin (0, 2 g/kg), puerain (0, 2.5 g/kg) and the interaction between them, respectively. Twenty-four Landrace sows (similar parity and due date) were selected and randomly divided into four groups (control group, vaccarin group, puerain group and mixed group) and each group had six pigs. The pre-experimental period lasted for 7 days, and the experimental period lasted for 21 days. The results showed follows:1) the average daily feed intake of sows of mixed group was significantly higher than that of control group (P<0.05). Compare with control group, the average daily gain of all add groups at the second weeks had the trend of increasing, and the average daily gain in mixed group was significantly higher than that of control group (P<0.05). The content of insulin-like growth factor Ⅰ (IGF-Ⅰ) in milk of all add groups was significantly higher than that of control group (P<0.05), and had significant difference among all groups (P<0.05). 2) The content of growth hormone at the 1st, 10th and 21st days, estrogen at the 21st days and prolactin at the 1st, 10th and 21st days in serum of mixed group were significantly higher than those of control group (P<0.05). 3) The serum glutathione peroxidase activity at the 10th and 21st days of all add groups was significantly higher than that of control group (P<0.05), and the serum malondialdehyde content at the 1st, 10th and 21st days was significantly lower than that of control group (P<0.05). The serum total superoxide dismutase activity at the 1st, 10th and 21st days of mixed group was significantly higher than that of control group (P<0.05). In conclusion, under this experimental condition, diet added with vaccarin and puerain increase the lactation of sows and the content of prolactin, growth hormone and the activity of total superoxide dismutase in serum. The lactation performance, serum hormone and antioxidant indexes of lactating sow are improved.

Key words： vaccarin; puerain; lactation performance; antioxidant

Cite this article

WANG Fangfang , WU Hongzhi , DIAO Huajie , WANG Zhilong , DENG Xiaomin , DIAO Xinping . Effects of Vaccarin and Puerain on Lactation Performance, Serum Hormone and Antioxidant Indexes of Lactating Sows[J]. Chinese Journal of Animal Nutrition, 2016 , 28(12) : 3977 -3987 . DOI: 10.3969/j.issn.1006-267x.2016.12.032

References

[1] 丁月云.王不留行、黄芪对奶牛乳腺上皮细胞体外增殖与分泌功能影响的研究[D].博士学位论文.南京:南京农业大学,2008:120-121.

[2] 陈宜忠,吴德峰,黄志勇,等.中草药对香豚猪母猪的哺乳与繁殖性能的影响[J].中兽医学杂志,2015(3):16-19.

[3] 孙明梅.中草药饲料添加剂对哺乳母猪生产性能的影响[D].硕士学位论文.延边:延边大学,2007:12-17.

[4] 满晨,干小英,杨建涛.日粮中添加葛根粉对奶牛生产性能的影响[J].中国奶牛,2009(8):24-26.

[5] 郑高利,张信岳,郑经纬,等.葛根素和葛根总异黄酮的雌激素样活性[J].中药材,2002,25(8):566-568.

[6] 王亮.葛根素对小鼠生长激素和催乳素含量及其受体表达量的影响[D].硕士学位论文.呼和浩特:内蒙古农业大学,2013:9-12.

[7] LAWLOR P G,LYNCH P B,GARDINER G E,et al.Effect of liquid feeding weaned pigs on growth performance to harvest[J].Journal of Animal Science,2002,80(7):1725-1735.

[8] 张元中.中草药饲料添加剂对哺乳母猪生产性能的影响[D].硕士学位论文.郑州:河南农业大学,2010:13-15.

[9] 刘英姿,董筱萍,程迪,等.复方中草药添加剂对繁殖母猪生产性能及免疫功能影响的研究[J].饲料研究,2014(3):22-24.

[10] 陈丰,蒋宗勇,林映才.大豆异黄酮对哺乳母猪生产性能及抗氧化性能的影响[J].饲料博览,2010(8):1-5.

[11] 王建辰.家畜生殖内分泌学[M].北京:农业出版社,1993:58-60.

[12] LEONOUDAKIS D,SINGH M,MOHAJEK R,et al.Dystrogly can controls signaling of multiple hormones through modulation of STAT5 activity[J].Journal of Cell Science,2010,123(21):3683-3692.

[13] 李楠,高学军,关力.中药王不留行对奶牛乳腺细胞增殖及泌乳的影响[J].中国畜牧兽医,2011,38(6):45-48.

[14] TONG H L,GAO X J,LI Q Z,et al.Metabolic regulation of mammary gland epithelial cells of dairy cow by galactopoietic compound isolated from Vaccariae segetalis[J].Agricultural Sciences in China,2011,10(7):1106-1116.

[15] 王月影,王艳玲,李和平,等.动物乳腺发育的调控[J].畜牧与兽医,2002,34(7):36-38.

[16] KLEINBERG D L,RUAN W F.IGF-Ⅰ,GH and sex steroid effects in normal mammary gland development[J].Journal of Mammary Gland Biology and Neoplasia,2008,13(4):353-360.

[17] 高靖,高腾云,王荷香.葛根提取物对奶牛生产性能和血液生化指标的影响[J].中国畜牧兽医,2012,39(7):126-128.

[18] 李德生,方正锋,车炼强,等.饲粮添加王不留行与大豆异黄酮对泌乳母猪生产性能和抗氧化能力的影响[J].中国畜牧杂志,2014,50(1):63-68.

[19] BELL A W.Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation[J].Journal of Animal Science,1995,73(9):2804-2819.

[20] CASTILLO C,HERNANDEZ J,BRAVO A,et al.Oxidative status during late pregnancy and early lactation in dairy cows[J].The Veterinary Journal,2005,169(2):286-292.

[21] CASTILLO C,HERNÁNDEZ J,VALVERDE I,et al.Plasma malonaldehyde (MDA) and total antioxidant status (TAS) during lactation in dairy cows[J].Research in Veterinary Science,2006,80(2):133-139.

[22] DOEPEL L,LAPIERRE H,KENNELLY J J.Peripartum performance and metabolism of dairy COWS in response to prepartum energy and protein intake[J].Journal of Dairy Science,2002,85(9):2315-2334.

[23] CUZZOCREA S,RILEY D P,CAPUTI A P,et al.Antioxidant therapy:a new pharmacological approach in shock,inflammation,and ischemia/reperfusion injury[J].Pharmacological Reviews,2001,53(1):135-159.

[24] FANG Y Z,YANG S,WU G Y.Free radicals,antioxidants,and nutrition[J].Nutrition,2002,18(10):872-879.

[25] VASSALLE C,LUBRANO V,L'ABBATE A,et al.Determination of nitrite plus nitrate and malondialdehyde in human plasma:analytical performance and the effect of smoking and exercise[J].Clinical Chemistry and Laboratory Medicine,2002,40(8):802-809.

[26] 陈强,樊兆斌,梁军生,等.白术等复方中草药对断奶仔猪抗氧化功能的影响[J].饲料研究,2013(6):60-61.

[27] 周本宏,刘刚,罗顺德.葛根素对红细胞膜脂质过氧化损伤的防护作用[J].中国医院药学杂志,2004,24(8):470-472.

[28] 徐晓红.葛根素抗D-半乳糖致衰老小鼠的脂质过氧化作用[J].中国中药杂志,2003,28(1):66-69.

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