The Metabolism of Polyunsaturated Fatty Acids and Its Regulation to Inflammation

GONG Jian; XIAO Min

doi:10.3969/j.issn.1006-267x.2017.01.001

Chinese Journal of Animal Nutrition >

2017 , Vol. 29 >Issue 1: 1 - 7

DOI: https://doi.org/10.3969/j.issn.1006-267x.2017.01.001

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The Metabolism of Polyunsaturated Fatty Acids and Its Regulation to Inflammation

GONG Jian ,
XIAO Min

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College of Life Science and Technology, Inner Mongolia Normal University, Huhhot 010022, China

Received date: 2016-07-14

Online published: 2017-01-16

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Abstract

Inflammation is part of protective response to infection or tissue injury. Appropriate or controlled inflammation is necessary to eliminate invading pathogens and repair damaged tissue. However, excessive or uncontrolled inflammation contributes to a range of pathological inflammatory responses, which may result in the increased incidence of both metabolic and infectious diseases. Lipid mediators derived from polyunsaturated fatty acids have important roles in regulating the initiation, development and resolving of inflammatory responses. A better understanding of the metabolism of polyunsaturated fatty acids and its regulation to inflammation will facilitate the development of dietary nutritional strategies to control the incidence of diseases and improve human and animal health. Therefore, the metabolic pathways of polyunsaturated fatty acids and the regulatory mechanism of its metabolic products to inflammation were reviewed in this paper.

Key words： polyunsaturated fatty acids; metabolism; lipid mediators; inflammation

Cite this article

GONG Jian , XIAO Min . The Metabolism of Polyunsaturated Fatty Acids and Its Regulation to Inflammation[J]. Chinese Journal of Animal Nutrition, 2017 , 29(1) : 1 -7 . DOI: 10.3969/j.issn.1006-267x.2017.01.001

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