REVIEW

MicroRNAs: Effects on Intestinal Health and Its Mechanisms

  • CHEN Fang ,
  • ZHANG Hao ,
  • WEI Jintao ,
  • YANG Xuehai ,
  • ZHAO Na ,
  • ZHANG Wei
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  • Hubei Key Laboratory of Animal Embroyo Engineering and Molecular Breeding, Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan 430064, China

Received date: 2016-07-14

  Online published: 2017-01-16

Abstract

Intestine is the major organ of digesting and absorbing nutrients and plays an important role in protecting body against from bacterial infection. MicroRNAs (miRNAs) serve as important intracellular factor in post-transcriptional regulation of gene expression. In this paper, in order to provide reference for further study, we summarized recent researches in the expression of miRNAs in intestinal tissue, the effects of miRNAs on proliferation, differentiation and apoptosis of intestinal cells, the regulatory function on nutrient metabolism, intestinal barrier function and disease progression, and the absorption of external miRNAs in intestine.

Key words: miRNAs; intestine; effect; mechanism

Cite this article

CHEN Fang , ZHANG Hao , WEI Jintao , YANG Xuehai , ZHAO Na , ZHANG Wei . MicroRNAs: Effects on Intestinal Health and Its Mechanisms[J]. Chinese Journal of Animal Nutrition, 2017 , 29(1) : 21 -26 . DOI: 10.3969/j.issn.1006-267x.2017.01.003

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