Evaluation on Tolerance of Arbor Acres Broilers to Guanidinoacetic Acid

ZHANG Defu, LI Juntao, TIAN Yaoyao, YANG Libin, ZHANG Liying

doi:10.3969/j.issn.1006-267x.2017.02.013

Chinese Journal of Animal Nutrition >

2017 , Vol. 29 >Issue 2: 456 - 464

DOI: https://doi.org/10.3969/j.issn.1006-267x.2017.02.013

Molecular Nutrition

Evaluation on Tolerance of Arbor Acres Broilers to Guanidinoacetic Acid

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1. Ministry of Agriculture Feed Efficacy and Safety Evaluation Center, State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, China;
2. Beijing Gendone Agricultural Technology Co., Ltd., Beijing 100085, China

Received date: 2016-07-18

Online published: 2017-02-17

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Abstract

This experiment was conducted to study the effects of guanidinoacetic acid (GAA) supplementation on growth performance, haematological indice, organ indices, tissue homocysteine contents and histomorphology, and to systematically evaluate the tolerance of Arbor Acres (AA) broilers to GAA. A total of 540 one-day-old AA male broilers were randomly divided into five groups with six replicates and eighteen broilers per replicate. Broilers were fed the same basal diet supplemented with 0 (control), 800, 1 600, 4 000 and 8 000 mg/kg GAA for 42 days, respectively. The experimental period consisted of earlier stage (aged from 1 to 21 days) and later stage (aged from 22 to 42 days). The results showed that compared with control group, GAA supplementation at 800~4 000 mg/kg significantly increased average daily gain of broilers during earlier, later and overall periods (P<0.05), and significantly decreased the ratio of feed to gain during later and overall periods (P<0.05). However, average daily feed intake had no significant difference among groups during either period (P>0.05). GAA supplementation at 8 000 mg/kg did not significantly affect average daily gain, average daily feed intake, and the ratio of feed to gain (P>0.05). Dietary GAA supplementation had no significant effects on blood routine indices and serum biochemical parameters, organ indices, and tissue homocysteine content of broilers aged of 21 and 42 days (P>0.05). GAA supplementation at 4 000 and 8 000 mg/kg had no adverse effects on liver and kidney morphology of broilers. In conclusion, dietary GAA supplementation has no adverse effects on growth performance, haematological indices, organ indices, tissue homocysteine content and histomorphology of broilers. Broilers have a good tolerance to GAA at the level of 8 000 mg/kg.

Key words： guanidinoacetic acid; broilers; tolerance; growth performance; haematological indices; organ indices; homocysteine

Cite this article

ZHANG Defu, LI Juntao, TIAN Yaoyao, YANG Libin, ZHANG Liying . Evaluation on Tolerance of Arbor Acres Broilers to Guanidinoacetic Acid[J]. Chinese Journal of Animal Nutrition, 2017 , 29(2) : 456 -464 . DOI: 10.3969/j.issn.1006-267x.2017.02.013

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